| Name | glutathione reductase |
|---|---|
| Synonyms | GLUR; GR; GRD 1; GRD1; GRase; GSR; Glutathione reductase; GRases… |
| Name | hexachlorobenzene |
|---|---|
| CAS | 1,2,3,4,5,6-hexachlorobenzene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12038708 | Iscan M, Coban T, Cok I, Bulbul D, Eke BC, Burgaz S: The organochlorine pesticide residues and antioxidant enzyme activities in human breast tumors: is there any association?. Breast Cancer Res Treat. 2002 Mar;72(2):173-82. The levels of some organochlorine pesticides (OCP) s (hexachlorobenzene, HCB, alpha-hexachlorocyclohexane, alpha-HCH, beta-HCH, gamma-HCH, heptachlorepoxide, HE, bis (4-chlorophenyl)-1,1-dichloroethene, p.p'DDE, bis (4-chlorophenyl)-1,1,1-trichloroethane, p.p' DDT and total DDT (E-DDT) and antioxidant enzyme activities namely Cu, Zn superoxide dismutase (SOD), catalase (CAT), -dependent peroxidase (Se--Px), total peroxidase (T--Px), independent peroxidase -Px II), glutathione reductase (GRd), level of and lipid peroxidation (LP), glutathione S-transferase (GST) activity toward several substrates including 1-chloro-2,4-dinitrobenzene (CDNB), 1,2-dichloro-4-nitrobenzene (DCNB), ethacrynic acid (EAA), 1,2-epoxy-3-(p-nitrophenoxy)-propane (ENPP) were measured in tumor and surrounding tumor free tissues of 24 female breast cancer patients and was evaluated whether there exist any association between the levels of OCPs and antioxidants. |
31(0,1,1,1) | Details |
| 17618397 | Elia AC, Dorr AJ, Galarini R: Comparison of organochlorine pesticides, PCBs, and heavy metal contamination and of detoxifying response in tissues of Ameiurus melas from Corbara, Alviano, and Trasimeno Lakes, Italy. Bull Environ Contam Toxicol. 2007 Jun;78(6):463-8. Epub 2007 Jul 7. Accumulation of cadmium (Cd), mercury (Hg), lead (Pb), (Cr), hexachlorobenzene, gamma-HCH, DDTs, and PCBs has been investigated in the muscle of Ameiurus melas sampled during the same period from Lake Corbara, Alviano, and Trasimeno. content and the enzymatic activities of glutathione reductase, peroxidase, catalase, glutathione S-transferase, and glyoxalase I were examined in gills, liver, and kidneys of each specimen. |
1(0,0,0,1) | Details |
| 19954812 | Faria M, Huertas D, Soto DX, Grimalt JO, Catalan J, Riva MC, Barata C: Contaminant accumulation and multi-biomarker responses in field collected zebra mussels (Dreissena polymorpha) and crayfish (Procambarus clarkii), to evaluate toxicological effects of industrial hazardous dumps in the Ebro river (NE Spain). Chemosphere. 2010 Jan;78(3):232-40. Epub 2009 Dec 1. Biological responses included levels of metallothioneins, activities of ethoxyresorufin-O-deethylase, oxidative stress biomarkers content, enzymatic activities of superoxide dismutase, catalase, glutathione s-transferase, peroxidise and glutathione reductase), levels of lipid peroxidation and of DNA strand breaks. The aforementioned stress levels could be related with concentrations of mercury, cadmium, hexachlorobenzene, polychlorobiphenyls and dichlorodiphenyltrichloroethanes from 4- to 195-fold greater than local background levels. |
1(0,0,0,1) | Details |
| 9806169 | Thomas RS, Gustafson DL, Pott WA, Long ME, Benjamin SA, Yang RS: Evidence for hepatocarcinogenic activity of pentachlorobenzene with intralobular variation in foci incidence. Carcinogenesis. 1998 Oct;19(10):1855-62. Pentachlorobenzene (PeCB) is an important environmental contaminant derived primarily from the by-product contamination of the popular fungicides hexachlorobenzene and pentachloronitrobenzene. Glutathione reductase (GR) and gamma-glutamylcysteine synthetase (gamma-GCS) were both significantly induced in the centrilobular region. |
1(0,0,0,1) | Details |