Protein Information

Name lactate dehydrogenase (protein family or complex)
Synonyms LDH; lactate dehydrogenase; lactate dehydrogenases

Compound Information

Name mirex
CAS

Reference List

PubMed Abstract RScore(About this table)
1171129 Hendrickson CM, Bowden JA: The in vitro inhibition of rabbit muscle lactate dehydrogenase by Mirex and Kepone. J Agric Food Chem. 1975 May-Jun;23(3):407-9.
81(1,1,1,1) Details
9628554 Todoroff EC, Sevcik M, Villeneuve DC, Foster WG, Jarrell JF: The effect of photomirex on the in vitro perfused ovary of the rat. Reprod Toxicol. 1998 May-Jun;12(3):305-16.

Photomirex, a photodegradation product of the insecticide mirex, is an environmental contaminant that has been identified in Great Lakes fish, soil, and human adipose tissue.
Significant effects of perfusion and chemical intervention were identified using lactate dehydrogenase enzyme, glucose utilization, lactate, pyruvate, and flow:pressure ratio as markers of toxicity (P < 0.05).
1(0,0,0,1) Details
176188 Hendrickson CM, Bowden JA: In vitro inhibition of lactate dehydrogenase by insecticidal polychlorinated hydrocarbons. J Agric Food Chem. 1976 Mar-Apr;24(2):241-4.

Mechanism of inhibition: possible association of reduced nicotinamide adenine dinucleotide with Mirex.
1(0,0,0,1) Details