| Name | ornithine decarboxylase |
|---|---|
| Synonyms | ODC; ODC 1; ODC 2; ODC1; ODC1 protein; ODC2; ODCP; Ornithine decarboxylase… |
| Name | mirex |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2283661 | Mitra A, Richards I, Kitchin K, Conolly R, Kulkarni AP: Mirex induces ornithine decarboxylase in female rat liver. . J Biochem Toxicol. 1990 Summer;5(2):119-24. Ornithine decarboxylase, the rate-limiting enzyme in polyamine synthesis, was significantly induced in female rat liver following oral administration of the pesticide mirex. |
55(0,1,5,5) | Details |
| 3789152 | Yarbrough JD, Grimley JM, Karl PI: The relationship of ornithine decarboxylase and thymidine kinase to mirex-induced liver growth. Am J Physiol. 1986 Dec;251(6 Pt 1):G859-65. |
12(0,0,2,2) | Details |
| 7871547 | Dwivedi C, Tabbert J: Effects of methoxychlor on skin tumor development. Toxicol Lett. 1994 Dec;74(3):235-40. Mirex, an organochlorine pesticide has been shown to be a tumor promoter in mouse skin. In the present study, the effects of methoxychlor, a commonly used organochlorine pesticide, on the development of papillomas in 7,12-dimethylbenz [a] anthracene (DMBA)-initiated mouse skin and induction of mouse epidermal ornithine decarboxylase (ODC) activity were investigated and compared with 12-O-tetradecanoylphorbol-13- (TPA), a well-known tumor promoter. |
1(0,0,0,1) | Details |
| 7903485 | Kitchin KT, Brown JL, Kulkarni AP: Predicting rodent carcinogenicity of halogenated hydrocarbons by in vivo biochemical parameters. Teratog Carcinog Mutagen. 1993;13(4):167-84. The effects of these 40 chemicals on four biochemical assays [hepatic DNA damage by alkaline elution (DD), hepatic ornithine decarboxylase activity (ODC), serum alanine aminotransferase activity (ALT), and hepatic cytochrome P-450 content (P450)] were determined. For predicting the carcinogenicity of the most difficult halogenated hydrocarbons (Ames and SA negative chemicals), TS was capable of successfully predicting the carcinogenicity of 8 (carbon tetrachloride, chloroform, alpha-hexachlorocyclohexane, kepone, mirex, monuron, p,p'-DDE, and 2,4,6-trichlorophenol) out of 16 of these non-DNA-reactive halogenated hydrocarbon carcinogens. |
1(0,0,0,1) | Details |
| 1732051 | Moser GJ, Meyer SA, Smart RC: The chlorinated pesticide mirex is a novel nonphorbol ester-type tumor promoter in mouse skin. Cancer Res. 1992 Feb 1;52(3):631-6. |
0(0,0,0,0) | Details |
| 8013418 | Meyer SA, Moser GJ, Monteiro-Riviere NA, Smart RC: Minimal role of enhanced cell proliferation in skin tumor promotion by mirex: a nonphorbol ester-type promoter. Environ Health Perspect. 1993 Dec;101 Suppl 5:265-9. |
0(0,0,0,0) | Details |
| 6838646 | Bulger WH, Kupfer D: Effect of xenobiotic estrogens and structurally related compounds on 2-hydroxylation of and on other monooxygenase activities in rat liver. Biochem Pharmacol. 1983 Mar 15;32(6):1005-10. Administration of Kepone (estrogenic) and Mirex (nonestrogenic), both inducers of hepatic monooxygenase, also increased 2-hydroxylation of |
0(0,0,0,0) | Details |