Name | estrogen receptor |
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Synonyms | ER; ERA; ER alpha; ERalpha; ESR; ESR 1; ESR1; ESRA… |
Name | mirex |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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12215659 | Porter KL, Chanda S, Wang HQ, Gaido KW, Smart RC, Robinette CL: 17beta-mirex tumor promotion sensitivity in mice. Toxicol Sci. 2002 Sep;69(1):42-8. Consistent with a role for E2 and ERalpha and ERbeta, treatment of DMBA-initiated female mice with topical ICI 182,780, an estrogen-receptor antagonist, reduced mirex tumor multiplicity by 30%. |
is a hormonal regulator of 31(0,1,1,1) | Details |
12505301 | Guillette LJ Jr, Vonier PM, McLachlan JA: Affinity of the alligator estrogen receptor for serum pesticide contaminants. Toxicology. 2002 Dec 27;181-182:151-4. Two compounds, aldrin and Mirex showed little affinity for the aER. |
2(0,0,0,2) | Details |
12167306 | Okoumassoun LE, Averill-Bates D, Gagne F, Marion M, Denizeau F: Assessing the estrogenic potential of organochlorine pesticides in primary cultures of male rainbow trout (Oncorhynchus mykiss) hepatocytes using vitellogenin as a biomarker. Toxicology. 2002 Sep 16;178(3):193-207. Non-toxic levels of these compounds competed with E (2) for binding to the estrogen receptor. The aim of this study was to assess the estrogenic activity of the organochlorine pesticides o,p'-DDT, dieldrin, aldrin, heptachlor, mirex and DDT in rainbow trout hepatocyte cultures using vitellogenin (Vtg) as the biomarker. |
1(0,0,0,1) | Details |