Protein Information

Name ATPases
Synonyms (NA+ + K+)ATPase; ATP1A1; ATPase; ATPase Na+/K+ transporting alpha 1 polypeptide; Na (+) K (+) ATPase; Na (+),K (+) ATPase; Na + K + ATPase; Na K + ATPase…

Compound Information

Name mirex
CAS

Reference List

PubMed Abstract RScore(About this table)
35323 Mehendale HM, Ho IK, Desaiah D: Possible molecular mechanism of mirex-induced hepatobiliary dysfunction. Drug Metab Dispos. 1979 Jan-Feb;7(1):28-33.

Whereas mitochondrial Mg++-ATPase and microsomal Na+-K+-ATPase activities were both inhibited by exposure to mirex in a dose-dependent manner, the latter activity was consistently inhibited to a higher degree.
81(1,1,1,1) Details
6160190 Desaiah D: Comparative effects of chlordecone and mirex on rat cardiac ATPases and binding of 3H-catecholamines. J Environ Pathol Toxicol. 1980 Aug;4(1):237-48.
62(0,2,2,2) Details
6175765 Desaiah D: Interaction of chlordecone with biological membranes. . J Toxicol Environ Health. 1981 Nov-Dec;8(5-6):719-30.

Chlordecone (Kepone) is a close structural analog of mirex, but it differs considerably from mirex in toxic action.
An attempt is made in this paper to review the effects of chlordecone on the membrane-bound adenosinetriphosphatases (ATPases) and related phenomena.
5(0,0,0,5) Details