| Name | CGRP |
|---|---|
| Synonyms | Alpha type CGRP; CT; CGRP; CALC 1; CALC1; CALCA; CGRP 1; CGRP I… |
| Name | piperazine |
|---|---|
| CAS | piperazine |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16161996 | Rudolf K, Eberlein W, Engel W, Pieper H, Entzeroth M, Hallermayer G, Doods H: Development of human calcitonin gene-related peptide (CGRP) receptor antagonists. 1. J Med Chem. 2005 Sep 22;48(19):5921-31. Potent and selective small molecule CGRP antagonists. 1-[N2-[3,5-dibromo-N-[[4-(3,4-dihydro-2 (1H)-oxoquinazolin-3-yl)-1-piperidi nyl] carbonyl]-D-tyrosyl]-l-lysyl]-4-(4-pyridinyl) piperazine: the first CGRP antagonist for clinical trials in acute migraine.. |
37(0,1,1,7) | Details |
| 19469188 | Nieber K: [CGRP antagonists: novel concept for treatment of migraine] . Med Monatsschr Pharm. 2009 May;32(5):182-5. |
6(0,0,0,6) | Details |
| 16802852 | Troconiz IF, Wolters JM, Tillmann C, Schaefer HG, Roth W: Modelling the anti-migraine effects of BIBN 4096 BS: a new calcitonin gene-related peptide receptor antagonist. Clin Pharmacokinet. 2006;45(7):715-28. BACKGROUND AND OBJECTIVE: Migraine attacks are associated with release of the calcitonin gene-related peptide (CGRP) from trigeminal nerves. |
4(0,0,0,4) | Details |
| 17963849 | Doods H, Arndt K, Rudolf K, Just S: CGRP antagonists: unravelling the role of CGRP in migraine. . Trends Pharmacol Sci. 2007 Nov;28(11):580-7. Epub 2007 Oct 25. |
4(0,0,0,4) | Details |
| 18418734 | Owji AA, Chabot JG, Dumont Y, Quirion R: Adrenomedullin-2/intermedin induces cAMP accumulation in dissociated rat spinal cord cells: evidence for the existence of a distinct class of sites of action. J Mol Neurosci. 2008 Jul;35(3):355-61. Epub 2008 Apr 17. Adrenomedullin-2/intermedin is structurally related to the calcitonin family of peptides, which includes calcitonin gene-related peptide (CGRP), adrenomedullin, and amylin. |
4(0,0,0,4) | Details |