Protein Information

Name enkephalin
Synonyms Met enkephalin; enkephalin; M enkephalin

Compound Information

Name piperazine
CAS piperazine

Reference List

PubMed Abstract RScore(About this table)
15742360 D'Antuono M, de Guzman P, Kano T, Avoli M: Ripple activity in the dentate gyrus of dishinibited hippocampus-entorhinal cortex slices. J Neurosci Res. 2005 Apr 1;80(1):92-103.

Ripples, which were also recorded in "minislices" only of the dentate gyrus, were unaffected by application of the mu-opioid receptor agonist (D-Ala2-N-Me-Phe,Gly-ol) enkephalin (10 microM; n = 6) or the N-methyl-D-aspartate (NMDA) receptor antagonist 3-(2-carboxy-piperazine-4-yl)-propyl-l-phosphonate (10 microM; n = 5).
31(0,1,1,1) Details
16772768 Mosnaim AD, Ranade VV, Wolf ME, Puente J, Antonieta Valenzuela M: Phenothiazine molecule provides the basic chemical structure for various classes of pharmacotherapeutic agents. Am J Ther. 2006 May-Jun;13(3):261-73.

Synthetic phenothiazines (with aliphatic, methylpiperazine, piperazine-ethanol, piperazine-ethyl, or piperidine side-chain) and/or phenothiazine-derived agents e.g., thioxanthenes, benzepines, imonostilbenes, tricyclic antidepressants, dimetothiazine, and cyproheptadine have been effective in the treatment of a number of medical conditions with widely different etiology.
Some phenothiazines inhibit human plasmatic leucine-enkephalin aminopeptidase (s), enzymes known to regulate the turnover rate of a wide range of bioactive substances.
1(0,0,0,1) Details