| Name | c Jun N terminal kinase (protein family or complex) |
|---|---|
| Synonyms | c Jun N terminal kinase; JNK; c Jun NH (2) terminal kinase; Jun N terminal kinase |
| Name | piperazine |
|---|---|
| CAS | piperazine |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19433357 | Shin Y, Chen W, Habel J, Duckett D, Ling YY, Koenig M, He Y, Vojkovsky T, LoGrasso P, Kamenecka TM: Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3344-7. Epub 2009 Mar 26. |
32(0,1,1,2) | Details |
| 12354565 | Chen J, Shen C, Meller E: 5-HT1A receptor-mediated regulation of mitogen-activated protein kinase phosphorylation in rat brain. Eur J Pharmacol. 2002 Oct 4;452(2):155-62. The effect of 8-OH-DPAT was blocked by pretreatment with the selective 5-HT (1A) receptor antagonists N-[2-[4-(2-methoxyphenyl)-1-piperazinyl] ethyl]-N-2-pyridinylcyclohexanecar boxamide (WAY 100635), 1-(2-methoxyphenyl)-4-(4-[2-phthalimido] butyl) piperazine (NAN-190) and 4--N-(2-[4-(2-methoxyphenyl) 1-piperazinyl] ethyl)-N-(2-pyridinyl) benz amide dihydrochloride (p-MPPF), but not by the weak partial agonist/antagonist 8-(2-[4-(2-methoxyphenyl)-1-piperazinyl] ethyl)-8-azaspiro (4.5) decane-7,9-d ione dihydrochloride (BMY 7378). |
0(0,0,0,0) | Details |