Protein Information

Name muscles
Synonyms COX 7a M; COX VIIa M; COX7A; COX7A1; COX7A1 protein; COX7AH; COX7AM; Cytochrome c oxidase subunit 7a H…

Compound Information

Name endosulfan
CAS 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide

Reference List

PubMed Abstract RScore(About this table)
16538862 Benjamin N, Kushwah A, Sharma RK, Katiyar AK: Histopathological changes in liver, kidney and muscles of pesticides exposed malnourished and diabetic rats. Indian J Exp Biol. 2006 Mar;44(3):228-32.

Histopathological changes were observed in liver, kidney and muscles of normal, protein-malnourished, diabetic as well as both protein-malnourished and diabetic albino rats when exposed to a mixture of monocrotophos, hexachlorocyclohexane and endosulfan at varying intervals.
7(0,0,1,2) Details
17219236 Kuvarega AT, Taru P: Accumulation of endosulfan in wild rat, Rattus norvegious as a result of application to soya bean in Mazoe (Zimbabwe). Environ Monit Assess. 2007 Feb;125(1-3):333-45.

Levels of endosulfan in rats were found to range in livers from 0.356 to 5.807 ppb, in muscles from 0.089 to 5.167 ppb and in fatty tissues from 0.083 to 4.785 ppb.
13(0,0,2,3) Details
10846931 Falandysz J, Strandberg L, Mizera T, Kalisinska E: [The contamination of white-tailed sea eagles with organochlorines in Poland]. Rocz Panstw Zakl Hig. 2000;51(1):7-13.

The residues of PCBs, DDTs, HCHs, HCBz, PCBz, CHLs, aldrin, dieldrin, endrin, isodrin, endosulfan 1, endosulfan 2, mirex, TCPM-H and TCPM-OH were determined in breast muscles and an egg of white-tailed sea eagles collected in Poland in 1991-1995.
6(0,0,1,1) Details
2975512 Sharma RM: Effect of endosulfan on adenosine triphosphatase (ATPase) activity in liver, kidney, and muscles of Channa gachua. Bull Environ Contam Toxicol. 1988 Sep;41(3):317-23.
6(0,0,1,1) Details
2328352 Sharma RM: Effect of endosulfan on acid and alkaline phosphatase activity in liver, kidney, and muscles of Channa gachua. Bull Environ Contam Toxicol. 1990 Mar;44(3):443-8.
6(0,0,1,1) Details
19103455 Kalyoncu L, Agca I, Aktumsek A: Some organochlorine pesticide residues in fish species in Konya, Turkey. Chemosphere. 2009 Feb;74(7):885-9. Epub 2008 Dec 21.

However, dieldrin, endrin, beta endosulfan, p-p' DDT, and p-p' DDD were not found in Salmo trutta.
DDT and its metabolites and HCH were the predominant contaminants in fish muscles.
1(0,0,0,1) Details
11461840 van Wyk E, Bouwman H, van der Bank H, Verdoorn GH, Hofmann D: Persistent organochlorine pesticides detected in blood and tissue samples of vultures from different localities in South Africa. Comp Biochem Physiol C Toxicol Pharmacol. 2001 Jul;129(3):243-64.

Statistically significant (P <0.05) differences between populations were detected in geometric means calculated for gamma-BHC (lindane), alpha (cis)-chlordane and alpha-endosulfan.
Five of the organochlorine contaminants displayed significant variations between concentrations detected in the clotted blood, organs and muscles excised from vulture carcasses.
1(0,0,0,1) Details
2458634 Matsumoto K, Eldefrawi ME, Eldefrawi AT: Action of polychlorocycloalkane insecticides on binding of [35S] t-butylbicyclophosphorothionate to Torpedo electric organ membranes and stereospecificity of the binding site. Toxicol Appl Pharmacol. 1988 Sep 15;95(2):220-9.

Nevertheless, because of its high affinity for gamma-BHC such a protein in muscles or brain may be an important target for the action of this insecticide.
Endrin was more potent than dieldrin, but endosulfan I and II had similar effects.
1(0,0,0,1) Details
7314413 Anand M, Akveld AC, Saxena PR: Effect of a neurotic pesticide, endosulfan, on tissue blood flow in cats, including regional cerebral circulation. Vet Hum Toxicol. 1981 Aug;23(4):252-8.

The microsphere technique revealed that the cardiac output was preferentially redistributed to the heart and the brain at the cost of the fraction going to the kidneys, lungs, muscles and large intestine.
1(0,0,0,1) Details