| Name | glutathione reductase |
|---|---|
| Synonyms | GLUR; GR; GRD 1; GRD1; GRase; GSR; Glutathione reductase; GRases… |
| Name | endosulfan |
|---|---|
| CAS | 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7900959 | Naqvi SM, Vaishnavi C: Bioaccumulative potential and toxicity of endosulfan insecticide to non-target animals. Comp Biochem Physiol C. 1993 Jul;105(3):347-61. Endosulfan I (a metabolite) causes a significant change in and (b) Renal toxicity: inhibition of MFOs activity was noticed in rats; other effects included changes in proximal convoluted tubules and necrosis of the tubular epithelium. (c) Hepatotoxicity: chemically-induced aminopyrine N-demethylase and hydrolase were found in rat liver, and reduction in the level occurred. (d) Hematologic toxicity: endosulfan exposure resulted in a significant decrease in the level occurred. (d) Hematologic toxicity: endosulfan exposure resulted in a significant decrease in the erythrocyte glutathione reductase, hemoglobin amount, RBC number and mean corpuscular volume. 4. |
31(0,1,1,1) | Details |
| 2272657 | Kiran R, Varma MN: Age related toxic effects of endosulfan on certain enzymes of rat erythrocytes. Indian J Exp Biol. 1990 Jul;28(7):694-6. A significant decrease in the activity of erythrocyte glutathione reductase was observed in 30 and 70 days old rats whereas a significant increase in the activity of glucose-6-phosphate dehydrogenase (G-6-PD) was observed in these groups. |
2(0,0,0,2) | Details |
| 18179806 | Menone ML, Pesce SF, Diaz MP, Moreno VJ, Wunderlin DA: Endosulfan induces oxidative stress and changes on detoxication enzymes in the aquatic macrophyte Myriophyllum quitense. Phytochemistry. 2008 Mar;69(5):1150-7. Epub 2008 Jan 7. Thus, we measured the activities of catalase (CAT), soluble and membrane associated glutathione-S-transferases (s- and m-GSTs) and glutathione reductase (GR), as well as the peroxide (H2O2) content. |
1(0,0,0,1) | Details |
| 11701388 | Bayoumi AE, Garcia-Fernandez AJ, Ordonez C, Perez-Pertejo Y, Cubria JC, Reguera RM, Balana-Fouce R, Ordonez D: Cyclodiene organochlorine insecticide-induced alterations in the -redox cycle in CHO-K1 cells. Comp Biochem Physiol C Toxicol Pharmacol. 2001 Nov;130(3):315-23. The effect of the cyclodiene organochlorine pesticides aldrin, dieldrin and endosulfan was assessed on CHO-K1 cultures at fractions of their lethal doses, determined by the neutral red (NRI) incorporation assay (NRI6.25, NRI12.5 and NRI25). After a 24-h incubation with each insecticide, peroxidase incurred a large increase, while glutathione reductase and S-transferase activities were slightly higher than untreated controls. |
1(0,0,0,1) | Details |