Name | VLA 4 |
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Synonyms | CD49D; CD49d; CD49d antigen; IA4; ITGA 4; ITGA4; Integrin alpha 4; Integrin alpha IV… |
Name | piperazine |
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CAS | piperazine |
PubMed | Abstract | RScore(About this table) | |
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11865647 | Lewis I, Rohde B, Mengus M, Weetall M, Maida S, Hugo R, Lake P: Combinatorial approaches to inhibitors of VLA-4: piperazine-peptoid-bisarylureas. Mol Divers. 2000;5(2):61-73. |
31(0,1,1,1) | Details |
18160288 | Saku O, Ohta K, Arai E, Nomoto Y, Miura H, Nakamura H, Fuse E, Nakasato Y: Synthetic study of VLA-4/VCAM-1 inhibitors: synthesis and structure-activity relationship of piperazinylphenylalanine derivatives. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1053-7. Epub 2007 Dec 14. By changing components at the 4-position of piperazine and the terminal group of the amido bond, 12t was found to be the most potent of this series of compounds. |
2(0,0,0,2) | Details |