Protein Information

Name TERT
Synonyms ABG deleted variant of telomerase reverse transcriptase; EST 2; EST2; HEST 2; HEST2; TCS 1; TCS1; TERT…

Compound Information

Name endosulfan
CAS 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide

Reference List

PubMed Abstract RScore(About this table)
15832825 Je KH, Kim KN, Nam KW, Cho MH, Mar W: TERT mRNA expression is up-regulated in MCF-7 cells and a mouse mammary organ culture (MMOC) system by endosulfan treatment. Arch Pharm Res. 2005 Mar;28(3):351-7.

Also, transient expression assays using CAT reporter plasmids containing various fragments of the TERT promoter showed that this imperfect palindromic estrogen-responsive element is almost certainly responsible for the transcriptional activation by endosulfan.
44(0,1,3,4) Details