| Name | cytochrome c |
|---|---|
| Synonyms | CYC; CYCS; Cytochrome C; HCS; Cytochrome Cs |
| Name | endosulfan |
|---|---|
| CAS | 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6424426 | Sriram K, Misra UK: Interaction of endosulfan and dietary on rat hepatic drug metabolising enzymes. Acta Vitaminol Enzymol. 1983;5(4):213-8. Administration of (10,000 I.U./100 g body weight) daily for ten days reduced the activity of the above mentioned enzymes, when and endosulfan were given together, reduced the endosulfan induced increase of microsomal proteins and cytochrome P-450 levels, the activity of cytochrome C-reductase, aminopyrine N-demethylase and -hydroxylase. |
37(0,1,2,2) | Details |
| 4093546 | Tyagi SR, Sriram K, Narayan S, Misra UK: Induction of cytochrome P-450 and synthesis by endosulfan in liver of rats: effect of quality of dietary proteins. J Environ Sci Health B. 1985 Dec;20(6):651-64. Effect of endosulfan and actinomycin D either alone or together on microsomal protein, cytochrome P-450, cytochrome c reductase, hydroxylase, aminopyrine N-demethylase, content, incorporation of 3H- and 14C- were studied in rats given amino acid deficient and supplemented diets. |
6(0,0,1,1) | Details |
| 18831371 | Ramaneswari K, Rao LM: Influence of endosulfan and monocrotophos exposure on the activity of cytochrome C reductase (NCCR) of Labeo rohita (Ham). J Environ Biol. 2008 Mar;29(2):183-5. The results demonstrate that the pesticides, endosulfan and monocrotophos, interfere with dependent monoxygenase mechanism and are effective inducers of cytochrome C reductase. |
93(1,1,3,3) | Details |
| 10821422 | Kannan K, Holcombe RF, Jain SK, Alvarez-Hernandez X, Chervenak R, Wolf RE, Glass J: Evidence for the induction of apoptosis by endosulfan in a human T-cell leukemic line. Mol Cell Biochem. 2000 Feb;205(1-2):53-66. Based on these data, as well as those reported elsewhere, we propose the following sequence of events to account for T-cell apoptosis induced by endosulfan: uncoupling of oxidative phosphorylation --> excess ROS production --> GSH depletion --> oxidative stress --> disruption of deltapsim --> release of cytochrome C and other apoptosis related proteins to cytosol --> apoptosis. |
81(1,1,1,1) | Details |