Name | cAMP response element binding protein |
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Synonyms | Active transcription factor CREB; CREB; CREB 1; CREB1; cAMP response element binding protein; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP responsive element binding protein 1 isoform B… |
Name | piperazine |
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CAS | piperazine |
PubMed | Abstract | RScore(About this table) | |
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15700717 | Nikonova EV, Vijayasarathy C, Zhang L, Cater JR, Galante RJ, Ward SE, Avadhani NG, Pack AI: Differences in activity of cytochrome C oxidase in brain between sleep and wakefulness. Sleep. 2005 Jan 1;28(1):21-7. ABBREVIATIONS: ADP, ATP, COXI, cytochrome c oxidase subunit 1 mRNA; COX, cytochrome c oxidase (protein); CREB, cyclic AMP response element binding protein; DNA, deoxyribonucleic acid; EDTA, ethylenediaminetetraacetic acid; EEG, electroencephalography; EMG, electromyography; GABP, GA binding protein; HEPES, 4-(2-hydroxyethyl) piperazine-1-ethanesulfonic acid; mRNA, messenger ribonucleic acid; nicotinamid dinucleotide, reduced; NDII, NADH dehydrogenase subunit 2 mRNA; NRF, nuclear respiratory factor. |
31(0,1,1,1) | Details |
20164327 | Zhang J, Huang XY, Ye ML, Luo CX, Wu HY, Hu Y, Zhou QG, Wu DL, Zhu LJ, Zhu DY: Neuronal nitric oxide synthase alteration accounts for the role of 5-HT1A receptor in modulating anxiety-related behaviors. J Neurosci. 2010 Feb 17;30(7):2433-41. Blockade of hippocampal CREB phosphorylation by microinjection of H89 (5.19 microg/1.0 microl), a PKA (protein kinase A) inhibitor, abolished the anxiolytic-like effects of 7-NI (i.p., 30 mg/kg/d for 21 d). |
2(0,0,0,2) | Details |
19799970 | Smith VM, Hagel K, Antle MC: Serotonergic potentiation of photic phase shifts: examination of receptor contributions and early biochemical/molecular events. Neuroscience. 2010 Jan 13;165(1):16-27. Epub 2009 Sep 30. The mixed agonist/antagonist 1-(2-methoxyphenyl) 4-[4-(phthalimido) butyl]-piperazine hydrobromide (NAN-190) has been shown to greatly potentiate photic phase shifts in hamsters. Similarly, the levels of phosphorylated CREB protein, involved in a biochemical pathway leading to gene transcription, were also attenuated by NAN-190 in the wildtype mice. |
1(0,0,0,1) | Details |