Protein Information

Name sorbitol dehydrogenase
Synonyms L iditol 2 dehydrogenase; SORD; SORD 1; SORD 2; SORD1; SORD2; Sorbitol dehydrogenase; Sorbitol dehydrogenase 1…

Compound Information

Name endosulfan
CAS 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide

Reference List

PubMed Abstract RScore(About this table)
8588293 Sinha N, Narayan R, Shanker R, Saxena DK: Endosulfan-induced biochemical changes in the testis of rats. Vet Hum Toxicol. 1995 Dec;37(6):547-9.

Decreased sperm counts in the cauda epididymis and reduced intratesticular spermatid counts associated with elevation in the activities of specific testicular marker enzymes (sorbitol dehydrogenase, lactic dehydrogenase, gamma glutamyl transpeptidase, and glucose-6-phosphate dehydrogenase) were seen in all the endosulfan-dosed groups.
31(0,1,1,1) Details
11382554 Sinha N, Adhikari N, K Saxena D: Effect of endosulfan during fetal gonadal differentiation on spermatogenesis in rats. Environ Toxicol Pharmacol. 2001 Jun;10(1-2):29-32.

Exposure to endosulfan during fetal gonadal differentiation altered the process of spermatogenesis by affecting testicular lactate dehydrogenase and sorbitol dehydrogenase.
6(0,0,1,1) Details