Protein Information

Name CXCR3
Synonyms C X C chemokine receptor type 3; CD182; CD183; CD183 antigen; CKR L2; CMKAR 3; CMKAR3; CXC R3…

Compound Information

Name piperazine
CAS piperazine

Reference List

PubMed Abstract RScore(About this table)
19647429 McGuinness BF, Carroll CD, Zawacki LG, Dong G, Yang C, Hobbs DW, Jacob-Samuel B, Hall JW 3rd, Jenh CH, Kozlowski JA, Anilkumar GN, Rosenblum SB: Novel CXCR3 antagonists with a piperazinyl-piperidine core. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5205-8. Epub 2009 Jul 9.

High-throughput screening of an encoded combinatorial aryl piperazine library led to the identification of a novel series of potent piperazinyl-piperidine based CXCR3 antagonists.
33(0,1,1,3) Details