| Name | PAR2 |
|---|---|
| Synonyms | G protein coupled receptor 42; GPCR; PAR2; G protein coupled receptor 172B; GPCR42; GPR172B; PERV A receptor 2; Porcine endogenous retrovirus A receptor 2… |
| Name | piperazine |
|---|---|
| CAS | piperazine |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16260582 | Kelso EB, Lockhart JC, Hembrough T, Dunning L, Plevin R, Hollenberg MD, Sommerhoff CP, McLean JS, Ferrell WR: Therapeutic promise of proteinase-activated receptor-2 antagonism in joint inflammation. J Pharmacol Exp Ther. 2006 Mar;316(3):1017-24. Epub 2005 Oct 31. Finally, we report the activity of a novel small molecule PAR2 antagonist, N1-3-methylbutyryl-N4-6-aminohexanoyl-piperazine (ENMD-1068), that dose dependently attenuated joint inflammation. |
35(0,1,1,5) | Details |