| Name | Y5 receptors |
|---|---|
| Synonyms | NPY Y5 receptor; NPY5 R; NPY5R; NPYR 5; NPYR5; NPYY 5; NPYY5; Neuropeptide Y receptor Y5… |
| Name | piperazine |
|---|---|
| CAS | piperazine |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16919461 | Takahashi T, Sakuraba A, Hirohashi T, Shibata T, Hirose M, Haga Y, Nonoshita K, Kanno T, Ito J, Iwaasa H, Kanatani A, Fukami T, Sato N: Novel potent neuropeptide Y Y5 receptor antagonists: synthesis and structure-activity relationships of phenylpiperazine derivatives. Bioorg Med Chem. 2006 Nov 15;14(22):7501-11. Epub 2006 Aug 17. Subsequent optimization of the phenylpiperazine template by substitution of the phenyl moiety resulted in a series of (2-methanesulfonamidephenyl) piperazine derivatives that showed potent binding affinity and antagonistic activity for the Y5 receptor. |
83(1,1,1,3) | Details |
| 16750888 | Lall GS, Harrington ME: Potentiation of the resetting effects of light on circadian rhythms of hamsters using and neuropeptide Y receptor antagonists. Neuroscience. 2006 Sep 1;141(3):1545-52. Epub 2006 Jun 5. In this study we measured effects of compounds acting on serotonergic 1A and neuropeptide Y Y5 receptors to determine if combined serotonergic-neuropeptide Y inhibition could synergistically potentiate effects of light on rhythms. |
1(0,0,0,1) | Details |