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Weston AH, Feletou M, Vanhoutte PM, Falck JR, Campbell WB, Edwards G: Bradykinin-induced, endothelium-dependent responses in porcine coronary arteries: involvement of potassium channel activation and epoxyeicosatrienoic acids. Br J Pharmacol. 2005 Jul;145(6):775-84.
After gap junction blockade with HEPES, (N-(2-hydroxyethyl) piperazine-N'-(2-ethanesulphonic acid)) hyperpolarization of the endothelium by 100 nM bradykinin was abolished by TRAM-39 plus apamin, whereas myocyte hyperpolarization still occurred (12.9 +/- 1.0 mV, n=4). |
32(0,1,1,2) |
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