| Name | glycine receptor (protein family or complex) |
|---|---|
| Synonyms | Glycine receptor; Glycine receptors |
| Name | endosulfan |
|---|---|
| CAS | 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12614680 | Vale C, Fonfria E, Bujons J, Messeguer A, Rodriguez-Farre E, Sunol C: The organochlorine pesticides gamma-hexachlorocyclohexane (lindane), alpha-endosulfan and dieldrin differentially interact with (A) and -gated channels in primary cultures of cerebellar granule cells. Neuroscience. 2003;117(2):397-403. Lindane inhibited with similar potency both (A) (IC (50): 6.1 microM) and (5.0 microM) receptors. alpha-Endosulfan and dieldrin inhibited the (A) receptor (IC (50) values: 0.4 microM and 0.2 microM, respectively) more potently than the glycine receptor (IC (50) values: 3.5 microM and 3 microM, respectively). |
87(1,1,1,7) | Details |
| 9432128 | Turner KO, Syvanen M, Meizel S: The human acrosome reaction is highly sensitive to inhibition by cyclodiene insecticides. J Androl. 1997 Nov-Dec;18(6):571-5. It can be initiated in vitro by a putative physiological initiator that helps to activate sperm (A) receptor/ channels and by a substitute for the egg zona pellucida, which activates sperm glycine receptor/ channels. Even at 1 nM (0.41 ng/ml or 0.41 ppb), chlordane and endosulfan, chlorinated cyclodiene blockers of insect neuronal (A) receptor/ channels, strongly inhibited the AR initiated by or |
1(0,0,0,1) | Details |
| 10698677 | Kamijima M, Casida JE: Regional modification of [(3) H] Ethynylbicycloorthobenzoate binding in mouse brain (A) receptor by endosulfan, fipronil, and avermectin B (1a). Toxicol Appl Pharmacol. 2000 Mar 1;163(2):188-94. AVM increased [(3) H] EBOB binding in most regions and was the only one of the three agents inhibiting in vitro [(3) H] strychnine binding to the glycine receptor. |
1(0,0,0,1) | Details |