Protein Information

Name suppressor of cytokine signaling
Synonyms CIS; Cis1; CIS 1; CISH; Cytokine inducible SH2 containing protein; G18; Protein G18; SOCS…

Compound Information

Name piperazine
CAS piperazine

Reference List

PubMed Abstract RScore(About this table)
15146049 Lozovaya NA, Grebenyuk SE, Tsintsadze TSh, Feng B, Monaghan DT, Krishtal OA: Extrasynaptic NR2B and NR2D subunits of NMDA receptors shape 'superslow' afterburst EPSC in rat hippocampus. J Physiol. 2004 Jul 15;558(Pt 2):451-63. Epub 2004 May 14.

In contrast, ifenprodil, a highly selective NR2B antagonist, and [+/-]-cis-1-[phenanthren-2yl-carbonyl] piperazine-2,3-dicarboxylic acid (PPDA), a competitive antagonist that is moderately selective for NR2D subunits, more strongly inhibited the late component of the afterburst EPSC (NMDA).
31(0,1,1,1) Details
19193935 Guard DB, Swartz TD, Ritter RC, Burns GA, Covasa M: Blockade of hindbrain NMDA receptors containing NR2 subunits increases sucrose intake. Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R921-8. Epub 2009 Feb 4.

To test this, we measured deprivation-induced intake of 15% sucrose solution following fourth ventricle and intra-nucleus of the solitary tract (intra-NTS) injections of Conantokin G (Con G; NR2B blocker), d-3-(2-carboxypiperazin-4-yl)-1-propenyl-1-phosphoric acid (d-CPPene; NR2B/2A blocker), and (+/-)-cis-1-(phenanthren-2yl-carbonyl) piperazine-2,3-dicarboxylic acid (PPDA; NR2D/C blocker).
6(0,0,1,1) Details
11754267 Navarro M, Cisneros-Fajardo EJ, Lehmann T, Sanchez-Delgado RA, Atencio R, Silva P, Lira R, Urbina JA: Toward a novel metal-based chemotherapy against tropical diseases. 6. Inorg Chem. 2001 Dec 31;40(27):6879-84.

The complexes [Cu (CTZ)(4)] Cl (2).2H (2) O (1), [Cu (CTZ) Cl (2)](2) (2), [Cu (KTZ)(3) Cl (2)] (3), and [Cu (KTZ) Cl (2)](2).2H (2) O (4) were prepared by reaction of CuCl (2) with CTZ and KTZ (where CTZ = 1-[[(2-chlorophenyl) diphenyl] methyl]-1H-imidazole and KTZ = cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3- dioxolan-4-yl] methoxy] phenyl] piperazine), respectively, in acetonitrile at different ligand to metal molar ratios.
31(0,1,1,1) Details