| Name | brains |
|---|---|
| Synonyms | BPG dependent PGAM 1; Brain; CDABP0006; PGAM 1; PGAM B; PGAM1; PGAM1 protein; PGAMA… |
| Name | piperazine |
|---|---|
| CAS | piperazine |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15507542 | Raghavan N, Zhang D, Zhu M, Zeng J, Christopher L: Cyp2D6 catalyzes 5-hydroxylation of 1-(2-pyrimidinyl)-piperazine, an active metabolite of several psychoactive drugs, in human liver microsomes. Drug Metab Dispos. 2005 Feb;33(2):203-8. Epub 2004 Oct 26. 1-(2-Pyrimidinyl)-piperazine (1-PP) is an active metabolite of several psychoactive drugs including 1-PP is also the major metabolite in the human circulation and in rat brains following oral administration of |
81(1,1,1,1) | Details |
| 15860577 | Nightingale B, Dersch CM, Boos TL, Greiner E, Calhoun WJ, Jacobson AE, Rice KC, Rothman RB: Studies of the biogenic amine transporters. J Pharmacol Exp Ther. 2005 Aug;314(2):906-15. Epub 2005 Apr 28. Identification of a 1-[2-[bis (4-fluorophenyl) methoxy] ethyl]-4-(3-phenylpropyl) piperazine (GBR12909) analog that allosterically modulates the serotonin transporter.. Membranes were prepared from rat brains or human embryonic kidney cells expressing the cloned human (hDAT), (hSERT), and (hNET) transporters. beta-(4'-(125) Iodophenyl) tropan-2beta-carboxylic acid methyl ester ([(125) I] RTI-55) binding and other assays followed published procedures. |
1(0,0,0,1) | Details |
| 19425052 | Xu J, Chu W, Tu Z, Jones LA, Luedtke RR, Perlmutter JS, Mintun MA, Mach RH: [(3) H] 4-(Dimethylamino)-N-[4-(4-(2-methoxyphenyl) piperazin- 1-yl) butyl] benzamide, a selective radioligand for D (3) receptors. Synapse. 2009 Sep;63(9):717-28. 4-(Dimethylamino)-N-(4-(4-(2-methoxyphenyl) piperazin-1-yl) butyl) benzamide (WC-10), a N-phenyl piperazine analog, has been shown to have high affinity and selectivity for D (3) receptors versus D (2) receptors (Chu et al. [2005] Bioorg Med Chem 13:77-87). In vitro autoradiography studies of rat and monkey brains show that [(3) H] WC-10 labeled D (3) sites in the striatal region. |
1(0,0,0,1) | Details |
| 15138762 | Lee MD, Somerville EM, Kennett GA, Dourish CT, Clifton PG: Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor agonist mCPP in 5-HT1B receptor knockout mice. Psychopharmacology. 2004 Oct;176(1):39-49. Epub 2004 May 8. The binding of [3H]-mesulergine was compared in the brains of both mouse strains. |
1(0,0,0,1) | Details |
| 13679227 | Taffe MA, Huitron-Resendiz S, Schroeder R, Parsons LH, Henriksen SJ, Gold LH: MDMA exposure alters cognitive and electrophysiological sensitivity to rapid depletion in rhesus monkeys. Pharmacol Biochem Behav. 2003 Aug;76(1):141-52. Repeated treatment with (+/-) 3,4-methylenedioxymethamphetamine (MDMA) produces lasting depletions in markers in the brains of New and Old World monkeys. Those monkeys were, however, more behaviorally sensitive to challenge with the 5-HT (2C) agonist 1-(3-chlorophenyl) piperazine (mCPP ) 1 year after the MDMA regimen. |
1(0,0,0,1) | Details |