Name | Rhodanese |
---|---|
Synonyms | RDS; Rhodanese; TST; TST protein; Thiosulfate sulfurtransferase; Thiosulfate sulfurtransferase variant; thiosulfate sulfurtransferase (rhodanese); Rhodaneses… |
Name | hydrogen cyanide |
---|---|
CAS | hydrocyanic acid |
PubMed | Abstract | RScore(About this table) | |
---|---|---|---|
2006499 | Lewis JL, Rhoades CE, Gervasi PG, Griffith WC, Dahl AR: The metabolizing enzyme rhodanese in human nasal respiratory mucosa. Toxicol Appl Pharmacol. 1991 Mar 15;108(1):114-20. The high rhodanese activity in rat nasal epithelium may provide a mechanism for detoxicating inhaled hydrogen cyanide and may also play a role in olfaction by limiting the concentrations of in the nasal epithelium. |
-87(1,1,1,7) | Details |
2919401 | Dahl AR: The metabolizing enzyme rhodanese in rat nasal respiratory and olfactory mucosa. Toxicol Lett. 1989 Feb;45(2-3):199-205. Hydrogen cyanide is a commonly occurring and highly toxic air pollutant. |
-3(0,0,0,3) | Details |
19625201 | Zottola MA: A partial exploration of the potential energy surfaces of SCN and HSCN: implications for the enzyme-mediated detoxification of J Mol Graph Model. 2009 Sep;28(2):183-6. Epub 2009 Jul 4. The body uses the transferase enzyme rhodanese to detoxify via conversion of to This paper explores the potential energy surfaces for the conversion of anion and hydrogen cyanide to and respectively. |
1(0,0,0,1) | Details |
18199034 | Broderick KE, Chan A, Balasubramanian M, Feala J, Reed SL, Panda M, Sharma VS, Pilz RB, Bigby TD, Boss GR: Pseudomonas aeruginosa contributes to lethality in Drosophila melanogaster. J Infect Dis. 2008 Feb 1;197(3):457-64. P. aeruginosa PAO1 strain with a mutation in the hydrogen cyanide synthase gene cluster was much less toxic to flies than the parental cyanogenic strain or 2 knock-in strains. Transgenic flies overexpressing rhodanese, which detoxifies by converting it to were resistant to and the increased virulence of cyanogenic strains. |
produced by human isolates of 1(0,0,0,1) | Details |
16661359 | Miller JM, Conn EE: Metabolism of Hydrogen Cyanide by Higher Plants. Plant Physiol. 1980 Jun;65(6):1199-1202. The enzymes investigated were beta-cyanoalanine synthase, rhodanese and hydrolyase. beta-Cyanoalanine synthase was found to be present in every higher plant tested whereas rhodanese was found to occur far less commonly in plants. |
1(0,0,0,1) | Details |