| Name | PAO1 |
|---|---|
| Synonyms | Flavin containing amine oxidase; SMO; Flavin containing spermine oxidase; PAO; PAO 1; PAO1; PAOh1; Polyamine oxidase 1… |
| Name | hydrogen cyanide |
|---|---|
| CAS | hydrocyanic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15317771 | Lizewski SE, Schurr JR, Jackson DW, Frisk A, Carterson AJ, Schurr MJ: Identification of AlgR-regulated genes in Pseudomonas aeruginosa by use of microarray analysis. J Bacteriol. 2004 Sep;186(17):5672-84. Additionally, direct measurement of hydrogen cyanide (HCN) production showed that P. aeruginosa PAO1 produced threefold-less HCN than did its algR deletion strain. |
83(1,1,1,3) | Details |
| 11410352 | Pessi G, Haas D: Dual control of hydrogen cyanide biosynthesis by the global activator GacA in Pseudomonas aeruginosa PAO1. FEMS Microbiol Lett. 2001 Jun 12;200(1):73-8. The global response regulator GacA of Pseudomonas aeruginosa PAO1 positively controls the production of the quorum sensing signal molecule N-butanoyl--lactone (C4-HSL) and hence the synthesis of several C4-HSL-dependent virulence factors, including hydrogen cyanide (HCN). |
32(0,1,1,2) | Details |
| 12644493 | Heurlier K, Denervaud V, Pessi G, Reimmann C, Haas D: Negative control of quorum sensing by RpoN (sigma54) in Pseudomonas aeruginosa PAO1. J Bacteriol. 2003 Apr;185(7):2227-35. In Pseudomonas aeruginosa PAO1, the expression of several virulence factors such as elastase, rhamnolipids, and hydrogen cyanide depends on quorum-sensing regulation, which involves the lasRI and rhlRI systems controlled by N-(3-oxododecanoyl)- lactone and N-butyryl- lactone, respectively, as signal molecules. |
6(0,0,1,1) | Details |
| 18199034 | Broderick KE, Chan A, Balasubramanian M, Feala J, Reed SL, Panda M, Sharma VS, Pilz RB, Bigby TD, Boss GR: produced by human isolates of Pseudomonas aeruginosa contributes to lethality in Drosophila melanogaster. J Infect Dis. 2008 Feb 1;197(3):457-64. P. aeruginosa PAO1 strain with a mutation in the hydrogen cyanide synthase gene cluster was much less toxic to flies than the parental cyanogenic strain or 2 knock-in strains. |
6(0,0,1,1) | Details |
| 19721066 | Papaioannou E, Wahjudi M, Nadal-Jimenez P, Koch G, Setroikromo R, Quax WJ: Quorum-quenching acylase reduces the virulence of Pseudomonas aeruginosa in a Caenorhabditis elegans infection model. Antimicrob Agents Chemother. 2009 Nov;53(11):4891-7. Epub 2009 Aug 31. The Pseudomonas aeruginosa PAO1 gene pvdQ encodes an acyl- lactone (AHL) acylase capable of degrading N-(3-oxododecanoyl)- lactone by cleaving the AHL amide. |
5(0,0,0,5) | Details |
| 11591663 | Gallagher LA, Manoil C: Pseudomonas aeruginosa PAO1 kills Caenorhabditis elegans by poisoning. J Bacteriol. 2001 Nov;183(21):6207-14. Our results imply that hydrogen cyanide is the sole or primary toxic factor produced by P. aeruginosa that is responsible for killing of the nematode. |
3(0,0,0,3) | Details |
| 17766417 | Morici LA, Carterson AJ, Wagner VE, Frisk A, Schurr JR, Honer zu Bentrup K, Hassett DJ, Iglewski BH, Sauer K, Schurr MJ: Pseudomonas aeruginosa AlgR represses the Rhl quorum-sensing system in a biofilm-specific manner. J Bacteriol. 2007 Nov;189(21):7752-64. Epub 2007 Aug 31. AlgR controls numerous virulence factors in Pseudomonas aeruginosa, including alginate, hydrogen cyanide production, and type IV pilus-mediated twitching motility. Strain PSL317 (DeltaalgR) produced one-third the biofilm biomass of wild-type strain PAO1. |
3(0,0,0,3) | Details |
| 16436429 | Burrowes E, Baysse C, Adams C, O'Gara F: Influence of the regulatory protein RsmA on cellular functions in Pseudomonas aeruginosa PAO1, as revealed by transcriptome analysis. Microbiology. 2006 Feb;152(Pt 2):405-18. RsmA is a posttranscriptional regulatory protein in Pseudomonas aeruginosa that works in tandem with a small non-coding regulatory RNA molecule, RsmB (RsmZ), to regulate the expression of several virulence-related genes, including the N-acyl- lactone synthase genes lasI and rhlI, and the hydrogen cyanide and rhamnolipid biosynthetic operons. |
2(0,0,0,2) | Details |
| 11932439 | Reimmann C, Ginet N, Michel L, Keel C, Michaux P, Krishnapillai V, Zala M, Heurlier K, Triandafillu K, Harms H, Defago G, Haas D: Genetically programmed autoinducer destruction reduces virulence gene expression and swarming motility in Pseudomonas aeruginosa PAO1. Microbiology. 2002 Apr;148(Pt 4):923-32. This strongly reduced AHL content correlated with a markedly decreased expression and production of several virulence factors and cytotoxic compounds such as elastase, rhamnolipids, hydrogen cyanide and pyocyanin, and strongly reduced swarming. |
2(0,0,0,2) | Details |
| 17889392 | Zheng P, Sun J, Geffers R, Zeng AP: Functional characterization of the gene PA2384 in large-scale gene regulation in response to iron starvation in Pseudomonas aeruginosa. J Biotechnol. 2007 Dec 1;132(4):342-52. Epub 2007 Aug 14. The function unknown gene PA2384 of Pseudomonas aeruginosa PAO1 has been previously shown dramatically responsive to iron limitation. One hundred two quorum sensing (QS) dependent genes displayed differential transcriptions, including genes involved in the biosynthesis of some important virulence factors such as pyocyanin, rhamnolipids and hydrogen cyanide. |
2(0,0,0,2) | Details |
| 15126453 | Heurlier K, Williams F, Heeb S, Dormond C, Pessi G, Singer D, Camara M, Williams P, Haas D: Positive control of swarming, rhamnolipid synthesis, and lipase production by the posttranscriptional RsmA/RsmZ system in Pseudomonas aeruginosa PAO1. J Bacteriol. 2004 May;186(10):2936-45. In Pseudomonas aeruginosa, the small RNA-binding, regulatory protein RsmA is a negative control element in the formation of several extracellular products (e.g., pyocyanin, hydrogen cyanide, PA-IL lectin) as well as in the production of N-acylhomoserine lactone quorum-sensing signal molecules. |
1(0,0,0,1) | Details |
| 11092854 | Pessi G, Haas D: Transcriptional control of the hydrogen cyanide biosynthetic genes hcnABC by the anaerobic regulator ANR and the quorum-sensing regulators LasR and RhlR in Pseudomonas aeruginosa. J Bacteriol. 2000 Dec;182(24):6940-9. The hcnABC genes encoding HCN synthase were identified on a genomic fragment complementing an HCN-deficient mutant of P. aeruginosa PAO1. |
1(0,0,0,1) | Details |
| 19700524 | Hagins JM, Locy R, Silo-Suh L: lyase supplies precursors for hydrogen cyanide production in a cystic fibrosis isolate of Pseudomonas aeruginosa. J Bacteriol. 2009 Oct;191(20):6335-9. Epub 2009 Aug 21. |
0(0,0,0,0) | Details |