Protein Information

Name 3 beta HSD
Synonyms 3 Beta HSD 2; HSDB 3; HSDB3; 3 beta hydroxysteroid dehydrogenase; 3 beta HSD; 3Beta HSD II; HSD3B2; HSDB…

Compound Information

Name endosulfan
CAS 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide

Reference List

PubMed Abstract RScore(About this table)
2553591 Singh SK, Pandey RS: Gonadal toxicity of short term chronic endosulfan exposure to male rats. Indian J Exp Biol. 1989 Apr;27(4):341-6.

Endosulfan was studied for its effect on rat testicular toxicity in relation to the enzymes of androgen biosynthesis, viz. 3 beta-hydroxysteroid dehydrogenase (EC 1.1.1.145, 3 beta-HSD) and 17 beta-hydroxysteroid dehydrogenase (EC 1.1.1.64, 17 beta-HSD); cytosolic conjugation enzyme, glutathione-S-transferase (EC 2.5.1.18); and testicular as well as serum testosterone levels at the dose levels of 2.5, 5.0, 7.5 and 10 mg/kg body weight fed orally for 7 and 15 days.
31(0,1,1,1) Details