Protein Information

Name insulin like growth factor binding protein 3
Synonyms Acid stable subunit of the 140 K IGF complex; BP 53; Binding protein 29; Binding protein 53; Growth hormone dependent binding protein; IBP 3; IBP3; IGF binding protein 3…

Compound Information

Name nitrofen
CAS 2,4-dichloro-1-(4-nitrophenoxy)benzene

Reference List

PubMed Abstract RScore(About this table)
19844724 Ruttenstock E, Doi T, Dingemann J, Puri P: Downregulation of insulin-like growth factor binding protein 3 and 5 in nitrofen-induced pulmonary hypoplasia. Pediatr Surg Int. 2010 Jan;26(1):59-63.

CONCLUSION: Downregulation of IGFBP-3 and IGFBP-5 gene expression may cause pulmonary hypoplasia in the nitrofen-induced CDH model by interfering with retinoid signaling pathway.
51(0,1,4,6) Details