Protein Information

Name IL 6
Synonyms 26 kd protein; B cell differentiation factor; B cell stimulatory factor 2; BSF 2; BSF2; CDF; CTL differentiation factor; HGF…

Compound Information

Name endosulfan
CAS 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide

Reference List

PubMed Abstract RScore(About this table)
17261270 Han EH, Hwang YP, Kim HG, Jeong HG: Inflammatory effect of endosulfan via NF-kappaB activation in macrophages. . Biochem Biophys Res Commun. 2007 Apr 20;355(4):860-5. Epub 2007 Jan 22.

This study examined the effects of endosulfan on the production of nitric oxide (NO) and proinflammatory cytokines (IL-1beta, IL-6, TNF-alpha), and examined the molecular mechanism in macrophages.
81(1,1,1,1) Details
14975756 Sekine Y, Yamamoto T, Yumioka T, Imoto S, Kojima H, Matsuda T: Cross-talk between endocrine-disrupting chemicals and cytokine signaling through estrogen receptors. Biochem Biophys Res Commun. 2004 Mar 12;315(3):692-8.


STAT3 mainly acts as a signal transducer of IL-6 family cytokines and transcriptionally activates specific target genes.
1(0,0,0,1) Details