Protein Information

Name C18
Synonyms B1; D1; BBS 9; BBS9; BBS9 GENE; Bardet Biedl syndrome 9 protein; C18; PTH responsive osteosarcoma B1 protein…

Compound Information

Name cresol
CAS methylphenol

Reference List

PubMed Abstract RScore(About this table)
2380304 Suortti T: Determination of phenol in poly (vinyl chloride). . J Chromatogr. 1990 May 16;507:417-20.


The detection limit is about 10 mg phenol/kg PVC but may be easily increased ten-fold by gentle removal of tetrahydrofuran from the sample solution and cleaning of the sample with C18 cartridge, which allows the injection of larger volumes and thus improves sensitivity.
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2089061 Brega A, Prandini P, Amaglio C, Pafumi E: Determination of phenol, m-, o- and p-cresol, p-aminophenol and p-nitrophenol in urine by high-performance liquid chromatography. J Chromatogr. 1990 Dec 28;535(1-2):311-6.


The column was a reversed-phase Pecosphere 3 x 3 C18 Perkin Elmer; the mobile phase was a 30:70:0.1 (v/v/v) methanol-water-orthophosphoric acid mixture and the chromatogram was monitored at 215 nm.
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15560920 Eggenreich K, Zach E, Beck H, Wintersteiger R: Determination of 4-amino-m-cresol and 5-amino-o-cresol by high performance liquid chromatography and fluorescence derivatization using fluorescamine. J Biochem Biophys Methods. 2004 Oct 29;61(1-2):35-46.


For the determination of both compounds in aqueous biological matrices in order to simulate conditions for penetration studies with pig skin, a solid phase extraction procedure using C18 cartridges and acetonitrile (ACN) for elution could be developed.
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12475030 Orejuela E, Silva M: Sensitive determination of low molecular mass phenols by liquid chromatography with chemiluminescence detection for the determination of phenol and 4-methylphenol in urine. Analyst. 2002 Nov;127(11):1433-9.


The derivatives were successfully separated in 15 min on a C18 analytical column and determined using an integrated derivatization chemiluminescence detection unit based on the bis (2,4,6-trichlorophenyl) oxalate-hydrogen peroxide system.
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11510563 Pozo O, Pitarch E, Sancho JV, Hernandez F: Determination of the herbicide 4-chloro-2-methylphenoxyacetic acid and its main metabolite, 4-chloro-2-methylphenol in water and soil by liquid chromatography-electrospray tandem mass spectrometry. J Chromatogr A. 2001 Jul 20;923(1-2):75-85.


Soil samples were extracted in alkaline media and cleaned-up by solid-phase extraction with C18 cartridges before LC-MS analysis.
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17723759 Uzer A, Ercag E, Parlar H, Apak R, Filik H: Spectrophotometric determination of 4,6-dinitro-o-cresol (DNOC) in soil and lemon juice. Anal Chim Acta. 2006 Oct 27;580(1):83-90. Epub 2006 Jul 26.


Statistical comparison of the developed methods was made with the aid of high performance liquid chromatography (HPLC) equipped with a C18 (5 microm), 250 mm x 4.6 mm ID reversed phase column in conjunction with a UV (264 nm) detector, and a methanol (HPLC grade) +0.1% glacial acetic acid mixture mobile phase.
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6660505 Nomeir AA, Abou-Donia MB: High-performance liquid chromatographic analysis on radial compression column of the neurotoxic tri-o-cresyl phosphate and metabolites. Anal Biochem. 1983 Dec;135(2):296-303.


TOCP and its possible metabolites were analyzed on a reverse-phase C18 cartridge fitted into RCM-100 radial-compression separation system.
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15560919 Eggenreich K, Golouch S, Toscher B, Beck H, Kuehnelt D, Wintersteiger R: Determination of 4-amino-m-cresol and 5-amino-o-cresol and metabolites in human keratinocytes (HaCaT) by high-performance liquid chromatography with DAD and MS detection. J Biochem Biophys Methods. 2004 Oct 29;61(1-2):23-34.


After several pre-cleaning steps, further cleaning was done by solid-phase extraction using C18 phenyl cartridges.
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11938918 Zhang X, Wu R: [Analysis of phenolic compounds in mineral water by high performance liquid chromatography (HPLC)]. Se Pu. 1998 Nov;16(6):530-1.


The operating conditions were Turner C18, 5 microns, column, 150 mm x 4.6 mm i.d., mobile phase with V (ACN): V (water) = 40:60 for 10 min, then linear gradient elution for 25 min up to 80:20 with a flow rate of 1.3 mL/min.
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8004234 Bui MH: Simple determination of retinol, alpha-tocopherol and carotenoids (lutein, all-trans-lycopene, alpha- and beta-carotenes) in human plasma by isocratic liquid chromatography. J Chromatogr B Biomed Appl. 1994 Mar 18;654(1):129-33.


Aliquots (15 microliters) are injected onto a 250 x 4.6 mm I.D. column of Nucleosil 100-5 C18 with a pre-column of Lichrosorb RP-18, 7 microns, 15 x 3.2 mm I.D.
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