Name | FKBP12 |
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Synonyms | 12 kDa FKBP; PPIase; Rotamase; Peptidyl prolyl cis trans isomerase; FK506 binding protein 1; FK506 binding protein 12; FK506 binding protein 1A; FK506 binding protein 1A (12kD)… |
Name | cresol |
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CAS | methylphenol |
PubMed | Abstract | RScore(About this table) | |
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12443530 | George CH, Sorathia R, Bertrand BM, Lai FA: In situ modulation of the human cardiac ryanodine receptor (hRyR2) by FKBP12.6. Biochem J. 2003 Mar 1;370(Pt 2):579-89. The precise mode of interaction and modulation of the cardiac RyR (RyR2) channel by FKBP12/FKBP12.6 remains to be fully defined. The magnitude of Ca (2+) release in CHO (hRyR2) cells in response to stimulation by 4-chloro- m -cresol was in direct proportion to the expression levels of hRyR2. |
3(0,0,0,3) | Details |
11053126 | Fessenden JD, Wang Y, Moore RA, Chen SR, Allen PD, Pessah IN: Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line. Biophys J. 2000 Nov;79(5):2509-25. Western blot analysis with an FKBP12/12.6-selective antibody reveals that differences in gating behavior exhibited by RyR1 and RyR3 may be, in part, the result of lower affinity of RyR3 for FKBP12. |
2(0,0,0,2) | Details |