Protein Information

Name glutathione S transferase
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name cresol
CAS methylphenol

Reference List

PubMed Abstract RScore(About this table)
8579380 Kawamoto T, Koga M, Oyama T, Kodama Y: Habitual and genetic factors that affect urinary background levels of biomarkers for organic solvent exposure. Arch Environ Contam Toxicol. 1996 Jan;30(1):114-20.


The genotypes of five metabolizing enzymes, that is, low Km aldehyde dehydrogenase (ALDH2), polymorphic N-acetyl transferase (NAT2), cytochrome P-4501A1 (CYP1A1), cytochrome P-4502E1 (CYP2E1), and glutathione-S-transferase mu (GSTM1) were determined form peripheral blood samples.
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10875682 Boogaard PJ, de Kloe KP, Bierau J, Kuiken G, Borkulo PE, Watson WP, van Sittert NJ: Metabolic inactivation of five glycidyl ethers in lung and liver of humans, rats and mice in vitro. Xenobiotica. 2000 May;30(5):485-502.


However, GE may be metabolically inactivated in the body by two different enzymatic routes: conjugation of the epoxide moiety with the endogenous tripeptide glutathione (GSH) catalysed by glutathione S-transferase (GST) or hydrolysis of the epoxide moiety catalysed by epoxide hydrolase (EH). 2.
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2853418 Skoog MT, Nichols JS, Harrison BL, Wiseman JS: Specificity of an HPETE peroxidase from rat PMN. Prostaglandins. 1988 Sep;36(3):373-84.


The HPETE peroxidase could be a glutathione S-transferase selective for fatty acid hydroperoxides.
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6610071 Roebuck BD, MacMillan DL, Bush DM, Kensler TW: Modulation of azaserine-induced pancreatic foci by phenolic antioxidants in rats. J Natl Cancer Inst. 1984 Jun;72(6):1405-10.


The hepatic activities of glucose-6-phosphate dehydrogenase, glutathione reductase, and glutathione-S-transferases were markedly elevated while catalase and superoxide dismutase activities were unchanged.
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