Protein Information

Name parathyroid hormone
Synonyms PTH; Parathormone; Parathyrin; Parathyroid hormone; Parathyroid hormone precursor; Parathormones; Parathyrins; Parathyroid hormones…

Compound Information

Name cresol
CAS methylphenol

Reference List

PubMed Abstract RScore(About this table)
12631141 Canalejo A, Almaden Y, De Smet R, Glorieux G, Garfia B, Luque F, Vanholder R, Rodriguez M: Effects of uremic ultrafiltrate on the regulation of the parathyroid cell cycle by calcitriol. Kidney Int. 2003 Feb;63(2):732-7.


BACKGROUND: Calcitriol (CTR) is used in the treatment of hyperparathyroidism secondary to renal failure because it decreases parathyroid hormone (PTH) synthesis and parathyroid cell proliferation.
1(0,0,0,1) Details
9782569 Horl WH: Genesis of the uraemic syndrome: role of uraemic toxins. Wien Klin Wochenschr. 1998 Aug 21;110(15):511-20.


Parathyroid hormone satisfies the strict criteria of an uraemic toxin.
2(0,0,0,2) Details
2510066 Niwa T, Sobue G, Maeda K, Mitsuma T: Myoinositol inhibits proliferation of cultured Schwann cells: evidence for neurotoxicity of myoinositol. Nephrol Dial Transplant. 1989;4(7):662-6.


Myoinositol, methylguanidine, guanidinosuccinic acid, parathyroid hormone, phenol, p-cresol, 4-hydroxyphenylacetic acid, 4-hydroxybenzoic acid, and 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid were added at various concentrations to the culture medium.
1(0,0,0,1) Details
8734462 Haag-Weber M, Horl WH: Dysfunction of polymorphonuclear leukocytes in uremia. . Semin Nephrol. 1996 May;16(3):192-201.


Increased cytosolic calcium is associated with several alterations of PMNL function and metabolism, which improve by normalization of cytosolic calcium either by calcium channel blockers or by lowering of elevated parathyroid hormone.
1(0,0,0,1) Details