| Name | P glycoproteins |
|---|---|
| Synonyms | ABC20; MDR1; ABCB 1; ABCB1; ATP binding cassette sub family B member 1; CD243; CD243 antigen; CLCS… |
| Name | griseofulvin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19881305 | Hamid KA, Lin Y, Gao Y, Katsumi H, Sakane T, Yamamoto A: The effect of wellsolve, a novel solubilizing agent, on the intestinal barrier function and intestinal absorption of griseofulvin in rats. Biol Pharm Bull. 2009 Nov;32(11):1898-905. The model drugs used in this study were 5 (6)-carboxyfluorescein (CF), rhodamine123 (a P-glycoprotein substrate), cephalexin (a typical substrate for PEPT1) and griseofulvin (a BCS Class II drug). |
82(1,1,1,2) | Details |
| 8707270 | Preisegger KH, Stumptner C, Riegelnegg D, Brown PC, Silverman JA, Thorgeirsson SS, Denk H: Experimental Mallory body formation is accompanied by modulation of the expression of multidrug-resistance genes and their products. Hepatology. 1996 Jul;24(1):248-52. MBs can be produced in mouse liver by chronic administration of the porphyrinogenic drugs griseofulvin (GF) and 3,5-diethoxy-carbonyl-1,4-dihydrocollidine (DDC). We investigated the relationship between the mechanisms underlying the formation of MBs and the regulation of multidrug resistance (mdr) genes and their products, the P-glycoproteins (Pgp). |
1(0,0,0,1) | Details |
| 11826402 | Plosch T, Bloks VW, Baller JF, Havinga R, Verkade HJ, Jansen PL, Kuipers F: Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor in a griseofulvin-induced mouse model of erythropoietic protoporphyria. Hepatology. 2002 Feb;35(2):299-306. The aim of this study was to gain insight in the mode of biliary PP excretion, with emphasis on the potential contribution of the Mdr1 P-glycoprotein export pump and biliary lipids as PP carriers. |
1(0,0,0,1) | Details |