Protein Information

Name tissue transglutaminase
Synonyms Protein glutamine gamma glutamyltransferase 2; TG(C); TG2; TGC; TGM 2; TGM2; TGM2 protein; TGase C…

Compound Information

Name griseofulvin
CAS

Reference List

PubMed Abstract RScore(About this table)
18603402 Robin MA, Descatoire V, Pessayre D, Berson A: Steatohepatitis-inducing drugs trigger cytokeratin cross-links in hepatocytes. Toxicol In Vitro. 2008 Sep;22(6):1511-9. Epub 2008 Jul 7.

The formation of MDB has been previously reproduced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine or griseofulvin administration which cross-link CK8 by tissue transglutaminase, thus forming an entangled network, from which MDB progressively arise.
32(0,1,1,2) Details