| Name | E14 |
|---|---|
| Synonyms | E14; E14 gene; E14 protein; NPAT; NPAT protein; E14 genes; E14 proteins; NPAT proteins |
| Name | vinclozolin |
|---|---|
| CAS | 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16837734 | Anway MD, Memon MA, Uzumcu M, Skinner MK: Transgenerational effect of the endocrine disruptor vinclozolin on male spermatogenesis. J Androl. 2006 Nov-Dec;27(6):868-79. Epub 2006 Jul 12. The administration of vinclozolin, an androgen receptor antagonist, at 100 mg/kg/day from embryonic day 8-14 (E8-E14) of pregnancy to only the F0 dam resulted in a transgenerational phenotype in the subsequent male offspring in the F1-F4 generations. |
81(1,1,1,1) | Details |
| 18762243 | Anway MD, Rekow SS, Skinner MK: Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis. Reprod Toxicol. 2008 Oct;26(2):100-6. Epub 2008 Aug 13. The gestating female rats were exposed to intraperitoneal injections during embryonic day 8-14 (E8-E14) to 100mg/kg/day vinclozolin or flutamide at either 5mg or 20mg/kg/day. |
6(0,0,1,1) | Details |
| 15279874 | Uzumcu M, Suzuki H, Skinner MK: Effect of the anti-androgenic endocrine disruptor vinclozolin on embryonic testis cord formation and postnatal testis development and function. Reprod Toxicol. 2004 Aug-Sep;18(6):765-74. Pregnant rats were exposed to vinclozolin (100 mg/kg/day) between embryonic days 8 and 14 (E8-E14) of development. |
6(0,0,1,1) | Details |
| 18304984 | Nilsson EE, Anway MD, Stanfield J, Skinner MK: Transgenerational epigenetic effects of the endocrine disruptor vinclozolin on pregnancies and female adult onset disease. Reproduction. 2008 May;135(5):713-21. Epub 2008 Feb 27. Pregnant rats (F0 generation) were treated transiently with vinclozolin (i.e., fungicide with anti-androgenic activity) on embryonic (E) days E8-E14 of gestation. |
6(0,0,1,1) | Details |