Protein Information

Name apoprotein
Synonyms AD2; APOE; Apo E; Apolipoprotein E; Apolipoprotein E precursor; apoprotein; Apo Es; Apolipoprotein Es…

Compound Information

Name vinclozolin
CAS 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione

Reference List

PubMed Abstract RScore(About this table)
7986207 Ronis MJ, Ingelman-Sundberg M, Badger TM: Induction, suppression and inhibition of multiple hepatic cytochrome P450 isozymes in the male rat and bobwhite quail (Colinus virginianus) by ergosterol biosynthesis inhibiting fungicides (EBIFs). Biochem Pharmacol. 1994 Nov 16;48(10):1953-65.

In the current study, we examined the effects of two EBIFs in clinical use, clotrimazole and ketoconazole, and two agricultural EBIFs, propiconazole and vinclozolin, on hepatic monooxygenase activities and P450 apoprotein expression in the male Sprague-Dawley rat and the male bobwhite quail.
6(0,0,1,1) Details
9972464 Ronis MJ, Celander M, Badger TM: Cytochrome P450 enzymes in the kidney of the bobwhite quail (Colinus virginianus): induction and inhibition by ergosterol biosynthesis inhibiting fungicides. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1998 Nov;121(1-3):221-9.

Quail kidney microsomes also expressed high levels of a CYP 4A1 cross-reactive apoprotein which was inducible 3-4-fold by ketoconazole.
The effects of treatment with the fungicides: propiconazole, vinclozolin, clotrimazole and ketoconazole were examined.
1(0,0,0,1) Details