| Name | follicle stimulating hormone (protein family or complex) |
|---|---|
| Synonyms | Follicle stimulating hormone; Follitropin; Follitropins |
| Name | vinclozolin |
|---|---|
| CAS | 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10448550 | Foster WG, Desaulniers D, Leingartner K, Wade MG, Poon R, Chu I: Reproductive effects of tris (4-chlorophenyl) in the rat. Chemosphere. 1999 Aug;39(5):709-24. Serum concentrations of follicle stimulating hormone (FSH) in terminal blood samples were significantly (P < 0.02) elevated in the highest dose group compared to the controls. In addition, the calculated Ki (0.62 microM) for TCPM is lower than the reported Ki's for the antiandrogenic pesticides p,p'-DDE and vinclozolin. |
1(0,0,0,1) | Details |
| 19672408 | Eustache F, Mondon F, Canivenc-Lavier MC, Lesaffre C, Fulla Y, Berges R, Cravedi JP, Vaiman D, Auger J: Chronic dietary exposure to a low-dose mixture of and vinclozolin modifies the reproductive axis, testis transcriptome, and fertility. Environ Health Perspect. 2009 Aug;117(8):1272-9. Epub 2009 Apr 1. Functional clustering indicated that many of the genes induced belong to the "neuroactive ligand-receptor interactions" family encompassing several hormonally related actors (e.g., follicle-stimulating hormone and its receptor). |
1(0,0,0,1) | Details |
| 12563111 | Nellemann C, Dalgaard M, Lam HR, Vinggaard AM: The combined effects of vinclozolin and procymidone do not deviate from expected additivity in vitro and in vivo. Toxicol Sci. 2003 Feb;71(2):251-62. The levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH) were increased significantly with doses of 100 mg/kg vinclozolin and above. |
6(0,0,1,1) | Details |
| 12215663 | O'Connor JC, Frame SR, Ladics GS: Evaluation of a 15-day screening assay using intact male rats for identifying antiandrogens. Toxicol Sci. 2002 Sep;69(1):92-108. The endpoints evaluated included final body and organ weights (liver, thyroid gland, testes, epididymides, prostate, seminal vesicles with fluid, accessory sex gland unit [ASG]), serum hormone concentrations [T], [E2], [DHT], luteinizing hormone [LH], follicle stimulating hormone [FSH], prolactin [PRL], T (3), T (4), and thyroid stimulating hormone [TSH]), and histopathology of the testis, epididymis, and thyroid gland; positive results for each endpoint are described below. |
1(0,0,0,1) | Details |