Protein Information

Name glucose 6 phosphate dehydrogenase
Synonyms 6 phosphogluconolactonase; GDH; G6PDH; Glucose 6 phosphate dehydrogenase; GDH/6PGL endoplasmic bifunctional protein; GDH/6PGL endoplasmic bifunctional protein precursor; Glucose 1 dehydrogenase; Glucose dehydrogenase…

Compound Information

Name vinclozolin
CAS 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione

Reference List

PubMed Abstract RScore(About this table)
9726001 Lioi MB, Scarfi MR, Santoro A, Barbieri R, Zeni O, Di Berardino D, Ursini MV: Genotoxicity and oxidative stress induced by pesticide exposure in bovine lymphocyte cultures in vitro. Mutat Res. 1998 Jul 17;403(1-2):13-20.

The genotoxic activity of the pesticides gliphosate, vinclozolin and DPX-E9636 was studied in in vitro cultures of bovine lymphocytes, using chromosome aberration (CA) and sister chromatid exchange (SCE) frequencies as genetic end-points and a variation of glucose 6-phosphate dehydrogenase (G6PD) enzyme activity as a marker of changes in the normal cell redox state.
6(0,0,1,1) Details
9707097 Lioi MB, Scarfi MR, Santoro A, Barbieri R, Zeni O, Salvemini F, Di Berardino D, Ursini MV: Cytogenetic damage and induction of pro-oxidant state in human lymphocytes exposed in vitro to gliphosate, vinclozolin, atrazine, and DPX-E9636. Environ Mol Mutagen. 1998;32(1):39-46.

We analyzed chromosome aberrations (CAs), sister chromatid exchanges (SCEs), mitotic index (MI), and glucose 6-phosphate dehydrogenase (G6PD) enzyme activity in human peripheral lymphocytes from three healthy donors exposed in vitro to different concentrations of gliphosate, vinclozolin, atrazine, and DPX-E9636.
6(0,0,1,1) Details