Protein Information

Name peripheral type benzodiazepine receptor
Synonyms BZRP; Benzodiazapine receptor peripheral; DBI; IBP; MBR; Mitochondrial benzodiazepine receptor; PBR; PBRS…

Compound Information

Name lindane
CAS (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane

Reference List

PubMed Abstract RScore(About this table)
7491094 Zisterer DM, Sunol C, Moynagh PN, Williams DC, Rodriguez-Farre E: PK 11195 reduces the brain availability of lindane in rats and the convulsions induced by this neurotoxic agent. Life Sci. 1995;57(25):2359-64.

The effect of pretreatment with PK 11195, a ligand of the 'peripheral-type' benzodiazepine receptor (PBR), on convulsions induced by lindane (gamma-hexachlorocyclohexane, gamma-HCH) in rats was examined, to determine whether the mechanism of this convulsant activity may be mediated through the PBR.
31(0,1,1,1) Details