Protein Information

Name PC3
Synonyms CBX 8; PC3; CBX8; Chromobox homolog 8; Chromobox homolog 8 polycomb 3; Chromobox protein homolog 8; HPC 3; HPC3…

Compound Information

Name vinclozolin
CAS 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione

Reference List

PubMed Abstract RScore(About this table)
16621434 Kim HJ, Park YI, Dong MS: Comparison of prostate cancer cell lines for androgen receptor-mediated reporter gene assays. Toxicol In Vitro. 2006 Oct;20(7):1159-67. Epub 2006 Mar 8.

The transcriptional activity induced with 10 (-8) M DHT was inhibited about 50-75% in the PC3/AR (+) and 22Rv1, and 98% in the LNCaP, by vinclozolin.
34(0,1,1,4) Details