Protein Information

Name salivary peroxidase
Synonyms Airway lactoperoxidase; LPO; Lactoperoxidase; Lactoperoxidase precursor; SAPX; SPO; Salivary peroxidase; Lactoperoxidases…

Compound Information

Name potassium thiocyanate
CAS potassium thiocyanate

Reference List

PubMed Abstract RScore(About this table)
16787851 Tan FJ, Ockerman HW: Physical and sensory characteristics of marinated broiler drumsticks treated with lactoperoxidase system and thermal treatment. Br Poult Sci. 2006 Jun;47(3):281-5.

The LPS consisting of 1 microg/ml lactoperoxidase (LP), 5.9 mM potassium thiocyanate (KSCN) and 2.5 mM hydrogen peroxide (H2O2) was added to the marinade for the LPS treatments. 3.
8(0,0,1,3) Details
6589987 Tenovuo J, Larjava H: The protective effect of peroxidase and thiocyanate against hydrogen peroxide toxicity assessed by the uptake of [3H]-thymidine by human gingival fibroblasts cultured in vitro. Arch Oral Biol. 1984;29(6):445-51.


The hypothiocyanite ion (OSCN-) is the principal oxidation product of the salivary peroxidase-thiocyanate (SCN-)-hydrogen peroxide antimicrobial system.
3(0,0,0,3) Details
6706930 Magnusson RP, Taurog A, Dorris ML: Mechanism of iodide-dependent catalatic activity of thyroid peroxidase and lactoperoxidase. J Biol Chem. 1984 Jan 10;259(1):197-205.

3(0,0,0,3) Details
2045547 Shimazaki KA, Nishio N: Interacting properties of bovine lactoferrin with immobilized cibacron blue F3GA in column chromatography. J Dairy Sci. 1991 Feb;74(2):404-8.

Lactoferrin, adsorbed on the dye column, could not be eluted by 8 M urea, 1% Triton X-100, and 75% ethylene glycol, but was eluted by .1 M sodium hydroxide, 1 M potassium thiocyanate, 3 M potassium chloride, and free Cibacron blue F3GA.
The elution profile for lactoferrin differed from those of lactoperoxidase and serum albumin, which might allow efficient isolation of lactoferrin from whey via affinity chromatography.
1(0,0,0,1) Details
6976994 von Zabern I, Gigli I: Conformational changes in complement component C4 induced by activation, treatment with amines, chaotropes, or freezing-thawing, detectable by radioiodination using lactoperoxidase. J Immunol. 1982 Mar;128(3):1439-42.

2(0,0,0,2) Details
6578235 Mansson-Rahemtulla B, Pruitt KM, Tenovuo J, Le TM: A mouthrinse which optimizes in vivo generation of hypothiocyanite. J Dent Res. 1983 Oct;62(10):1062-6.

We report here the properties of a mouthrinse which enhances one of the natural defense factors in human saliva, the salivary peroxidase system.
Concentrations of the antimicrobial agent, the hypothiocyanite (OSCN-) ion, can be increased in vivo to bacteriostatic levels by use of a mouthrinse which is 4 mM (0.014%) in hydrogen peroxide and 1 mM (0.0097%) in potassium thiocyanate at pH 5.5.
1(0,0,0,1) Details