| PubMed |
Abstract |
RScore(About this table) |
| 15344313 |
Qin Y, Gao J, Zhang TT, Zhao L, Wu HW, Xu L, Xu JY, Lu SY: [Changes of thioredoxin mRNA level in neurons insulted by sodium azide] . Shi Yan Sheng Wu Xue Bao. 2002 Mar;35(1):26-30.
|
7(0,0,1,2) |
Details |
| 15133893 |
Zou Y, Gao J, Zhang TT, Xu L, Xu JY, Lu SY: [Changes of thioredoxin mRNA level in neurons with mitochondrial dysfunction insulted by H2O2]. Shi Yan Sheng Wu Xue Bao. 2004 Feb;37(1):15-21.
Sodium azide (NaN3) is a special inhibitor of mitochondrion cytochrome c oxidase (COX), which can be used to mimic neuronal damage induced by mitochondrial deficiency. |
2(0,0,0,2) |
Details |
| 17074421 |
Gao J, Zhu ZR, Ding HQ, Qian Z, Zhu L, Ke Y: Vulnerability of neurons with mitochondrial dysfunction to oxidative stress is associated with down-regulation of thioredoxin. Neurochem Int. 2007 Jan;50(2):379-85. Epub 2006 Oct 30.
In this study, we first developed an in vitro model of neuron with mitochondrial dysfunction, based on sodium azide (NaN (3))-induced inhibition of cytochrome c oxidase (complex IV) that is reduced in post-mortem AD brains, and then investigated the role of Trx expression in response of neurons with mitochondrial dysfunction to oxidative stress. |
2(0,0,0,2) |
Details |