| Name | MCT1 |
|---|---|
| Synonyms | CMA 1; MCT1; Mast cell protease I; CMA1; CYH; CYM; Chymase; Chymase 1… |
| Name | sodium azide |
|---|---|
| CAS | sodium azide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19505879 | Schneiderhan W, Scheler M, Holzmann KH, Marx M, Gschwend JE, Bucholz M, Gress TM, Seufferlein T, Adler G, Oswald F: CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models. Gut. 2009 Oct;58(10):1391-8. Epub 2009 Jun 7. Further induction of lactate production by sodium azide in MiaPaCa2 cells increased MCT1 as well as MCT4 expression. |
85(1,1,1,5) | Details |
| 15804185 | Majumdar S, Gunda S, Pal D, Mitra AK: Functional activity of a monocarboxylate transporter, MCT1, in the human retinal pigmented epithelium cell line, ARPE-19. Mol Pharm. 2005 Mar-Apr;2(2):109-17. Uptake was significantly decreased in the presence of sodium azide, ouabain, p-chloromercuribenzoic acid (pCMBA), N-ethylmaleamide, and p-chloromercuribenzene sulfonate (pCMBS). |
5(0,0,0,5) | Details |
| 19023563 | Goncalves P, Araujo JR, Pinho MJ, Martel F: Modulation of transport in Caco-2 cells. Naunyn Schmiedebergs Arch Pharmacol. 2009 Apr;379(4):325-36. Epub 2008 Nov 21. These characteristics are compatible with an involvement of MCT1-mediated transport. |
3(0,0,0,3) | Details |
| 18761711 | Maekawa F, Minehira K, Kadomatsu K, Pellerin L: Basal and stimulated lactate fluxes in primary cultures of astrocytes are differentially controlled by distinct proteins. J Neurochem. 2008 Nov;107(3):789-98. But more strikingly, enhancement of lactate efflux induced by was prevented while the effect of sodium azide was significantly reduced by treatment of cultured astrocytes with anti-basigin small interfering RNA. In conclusion, MCT1 plays a pivotal role in the control of basal -driven lactate flux in astrocytes while basigin is only partly involved, most likely via its interaction with MCT1. |
1(0,0,0,1) | Details |
| 12837486 | Legen I, Kristl A: pH and energy dependent transport of ketoprofen across rat jejunum in vitro. Eur J Pharm Biopharm. 2003 Jul;56(1):87-94. Mucosal-to-serosal permeability of ketoprofen increased three times when the pH of the incubation medium was changed from 8.06 (pH of the mucosal surface was 7.34) to 6.07 (pH of the mucosal surface was 5.95), while no pH dependence was found under ATP-depletion caused by sodium azide. |
0(0,0,0,0) | Details |