Protein Information

Name glutathione S transferase
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
10366541 Diah SK, Smitherman PK, Townsend AJ, Morrow CS: Detoxification of 1-chloro-2,4-dinitrobenzene in MCF7 breast cancer cells expressing glutathione S-transferase P1-1 and/or multidrug resistance protein 1. Toxicol Appl Pharmacol. 1999 Jun 1;157(2):85-93.

2(0,0,0,2) Details
18722362 Prigol M, Wilhelm EA, Schneider CC, Nogueira CW: Protective effect of unsymmetrical dichalcogenide, a novel antioxidant agent, in vitro and an in vivo model of brain oxidative damage. Chem Biol Interact. 2008 Nov 25;176(2-3):129-36. Epub 2008 Aug 5.

The levels of lipid peroxidation and the activity of catalase, glutathione peroxidase (GPx), glutathione S-transferase (GST) and glutathione reductase (GR) were carried out in brain homogenates of SNP-injected mice.
Unsymmetrical dichalcogenides (1-3) were tested against lipid peroxidation induced by sodium nitroprusside (SNP) or malonate, and reactive species (RS) production induced by sodium azide in rat brain homogenates.
1(0,0,0,1) Details
11483385 Shon YH, Nam KS: Antimutagenicity and induction of anticarcinogenic phase II enzymes by basidiomycetes. J Ethnopharmacol. 2001 Sep;77(1):103-9.

Extracts from Phellinus linteus, Phellinus igniarius, and Agrocybe cylindracea have been tested for their antimutagenic properties against direct-acting mutagens [4-nitro-o-phenylenediamine (NPD) and sodium azide (NaN (3))] and indirect-acting mutagens [2-aminofluorene (2-AF) and benzo [a] pyrene (B [a] P)], using the Salmonella typhimurium tester strains TA 98 and TA 100.
In addition, the chemopreventive potentials of these extracts to induce NAD (P) H:quinone oxidoreductase (QR) and glutathione S-transferase (GST) activities and glutathione (GSH) level extracts from the filtrate of the cultured broth of P. linteus, polysaccharide extracts from the cultured broth (PI I) and mycelia (PI II) and water extract of fruiting bodies (PI II) of P. igniarius, and polysaccharide extracts from the cultured broth (AC I) and mycelia (AC II) of A. cylindracea showed inhibitory effects on the mutagenic activities induced by the direct-acting mutagens, NPD and NaN (3), and the indirect-acting mutagens, 2-AF and B [a] P.
1(0,0,0,1) Details
10328762 Pai JJ, Kirkup MP, Frank EA, Pachter JA, Bryant RW: Compounds capable of generating singlet oxygen represent a source of artifactual data in scintillation proximity assays measuring phosphopeptide binding to SH2 domains. Anal Biochem. 1999 May 15;270(1):33-40.

The SPA used an antibody to couple glutathione-S-transferase SH2 domain fusion proteins to scintillant beads coated with protein A.
Their inhibitory activity was suppressed by the singlet oxygen scavengers sodium azide and dithiothreitol.
1(0,0,0,1) Details
17267090 Zodl B, Schmid D, Wassler G, Gundacker C, Leibetseder V, Thalhammer T, Ekmekcioglu C: Intestinal transport and metabolism of acrylamide. Toxicology. 2007 Mar 22;232(1-2):99-108. Epub 2006 Dec 22.

As the intestinal mechanisms of acrylamide absorption are poorly investigated we studied the transport of acrylamide in differentiated Caco-2 cells and its effects on biotransformation enzymes (CYP2E1 and glutathione S-transferase) and glutathione levels.
Predominantly, basal to apical transport was decreased when energy metabolism of the cells was inhibited by application of sodium azide and 2-deoxy-d-glucose.
1(0,0,0,1) Details