Name | lipase |
---|---|
Synonyms | HGL; HPL; HGL; Human giant larvae homolog; LGL 2; LGL2; LLGL 2; LLGL2… |
Name | sodium azide |
---|---|
CAS | sodium azide |
PubMed | Abstract | RScore(About this table) | |
---|---|---|---|
10634941 | Brasaemle DL, Levin DM, Adler-Wailes DC, Londos C: The lipolytic stimulation of 3T3-L1 adipocytes promotes the translocation of hormone-sensitive lipase to the surfaces of lipid storage droplets. Biochim Biophys Acta. 2000 Jan 17;1483(2):251-62. Hormone-sensitive lipase translocation and lipolysis were inhibited by N-ethylmaleimide and a combination of deoxyglucose and sodium azide. We propose that the major consequence of the phosphorylation of hormone-sensitive lipase following the lipolytic stimulation of adipocytes is the translocation of the lipase from the cytosol to the surfaces of lipid storage droplets. |
1(0,0,0,1) | Details |
12218047 | Jongbloed JD, Antelmann H, Hecker M, Nijland R, Bron S, Airaksinen U, Pries F, Quax WJ, van Dijl JM, Braun PG: Selective contribution of the twin-secretion in Bacillus subtilis. J Biol Chem. 2002 Nov 15;277(46):44068-78. Epub 2002 Sep 5. Sodium azide-inhibition of SecA strongly affected the extracellular appearance of de novo synthesized proteins, including the lipase LipA and two other proteins with predicted RR/KR-signal peptides. |
translocation pathway to protein 81(1,1,1,1) | Details |
15995648 | Kim DY, Kim HC, Kim SY, Rhee YH: Molecular characterization of extracellular medium-chain-length poly (3-hydroxyalkanoate) depolymerase genes from Pseudomonas alcaligenes strains. J Microbiol. 2005 Jun;43(3):285-94. The PhaZ (PalLB19) and the PhaZ (PalM4-7) commonly share the lipase box, GISSG, in their catalytic domains, and utilize 111Asn and 110Ser residues, respectively, as oxyanions that play an important role in transition-state stabilization of hydrolytic reactions. It was insensitive to sodium azide, and iodoacetamide, but susceptible to p-hydroxymercuribenzoic acid, N-bromosuccinimide, acetic anhydride, EDTA, diisopropyl fluorophosphate, phenylmethylsulfonyl Tween 80, and Triton X-100. |
1(0,0,0,1) | Details |
8130261 | Pinson A, Zilberman Y, Tirosh R, Trembovler V, Shohami E: High oligomycin concentrations augment 6-keto-PGF1 alpha production in ventricular cardiomyocytes. Biochim Biophys Acta. 1994 Mar 24;1211(3):283-8. In cells depleted of ATP, either by low oligomycin concentrations or by sodium azide, 6-keto PGF1 alpha was not appreciably increased. We suggest that oligomycin at high concentrations causes the release of free from phospholipids either by non-PIP2-specific PLC and DG lipase or by phospholipase D, phosphatidic acid phosphatase and DG lipase. |
1(0,0,0,1) | Details |
12576071 | Lata S, Bhardwaj K, Rajasekharan R: A single-step procedure for the synthesis of photoreactive and radioactive glycerolipids. Anal Biochem. 2003 Feb 1;313(1):155-9. Iodoazide was generated using [125I] iodomonochloride and sodium azide that was found to add stereospecifically in a variety of olefins. The synthesized radiolabeled photoprobes were subsequently used to label lipase and phospholipase A (2). |
1(0,0,0,1) | Details |