Protein Information

Name glucocorticoid receptor
Synonyms GCCR; GCR; GR; GRL; Glucocorticoid receptor; NR3C1; Glucocorticoid receptors

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
10938586 Elez D, Vidovic S, Matic G: The influence of hyperthermic stress on the redox state of glucocorticoid receptor. Stress. 2000 May;3(3):247-55.

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8120009 Hu LM, Bodwell J, Hu JM, Orti E, Munck A: Glucocorticoid receptors in ATP-depleted cells. J Biol Chem. 1994 Mar 4;269(9):6571-7.

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12117619 Sanner BM, Meder U, Zidek W, Tepel M: Effects of glucocorticoids on generation of reactive oxygen species in platelets. Steroids. 2002 Jul;67(8):715-9.

The inhibition of oxidative phosphorylation by sodium azide reduced platelets ROS to 8+/-1% (n=35).
The inhibitory effect of prednisolone or dexamethasone could also be observed in the presence of the glucocorticoid receptor inhibitor, mifepristone (RU486).
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