| 11259864 |
Toimela TA, Tahti H: Effects of mercuric chloride exposure on the glutamate uptake by cultured retinal pigment epithelial cells. Toxicol In Vitro. 2001 Feb;15(1):7-12.
The cytotoxicity caused by 15 min of exposure to mercuric chloride (0.01--1000 microM) was evaluated by WST-1 assay based on the activity of mitochondrial dehydrogenases. [(3) H] Glutamate uptake was measured after the cells were exposed to 0.1--100 microM mercuric chloride and the selected regulators of protein kinase C (PKC) pathway: PKC activator SC10, PKC inhibitor chelerythrine chloride, phospholipase A (2)/C inhibitor manoalide, tyrosine kinase inhibitor lavendustin A, competitive NMDA receptor antagonist AP7 and IP (3) receptor antagonist heparin. |
31(0,1,1,1) |
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