Protein Information

Name Hepatocyte growth factor
Synonyms F TCF; HGF; SF; Fibroblast derived tumor cytotoxic factor; HGFB; HPTA; Hepatocyte growth factor; Hepatocyte growth factor precursor…

Compound Information

Name mercuric chloride
CAS

Reference List

PubMed Abstract RScore(About this table)
15466269 Jo SK, Hu X, Yuen PS, Aslamkhan AG, Pritchard JB, Dear JW, Star RA: Delayed DMSO administration protects the kidney from mercuric chloride-induced injury. J Am Soc Nephrol. 2004 Oct;15(10):2648-54.

Whereas many agents can inhibit renal ischemic injury, only hepatocyte growth factor, melatonin, N-acetylcysteine, and DMSO inhibit injury after mercuric chloride administration.
81(1,1,1,1) Details
8183913 Kawaida K, Matsumoto K, Shimazu H, Nakamura T: Hepatocyte growth factor prevents acute renal failure and accelerates renal regeneration in mice. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4357-61.

2(0,0,0,2) Details
9918843 Kinosaki M, Yamaguchi K, Yamashita Y, Uematsu Y, Aihara H, Masunaga H, Morinaga T, Higashio K: A mutant of deleted variant of hepatocyte growth factor (dHGF) with alanine substitution in the N-terminal basic region has higher activity in vivo. Biochem Biophys Res Commun. 1999 Jan 19;254(2):363-7.

In addition, #2 reduced mortality of mercuric chloride-administered mice and the effect was stronger than that of dHGF.
2(0,0,0,2) Details
8342615 Igawa T, Matsumoto K, Kanda S, Saito Y, Nakamura T: Hepatocyte growth factor may function as a renotropic factor for regeneration in rats with acute renal injury. Am J Physiol. 1993 Jul;265(1 Pt 2):F61-9.

2(0,0,0,2) Details
11818705 Yamasaki N, Nagano T, Mori-Kudo I, Tsuchida A, Kawamura T, Seki H, Taiji M, Noguchi H: Hepatocyte growth factor protects functional and histological disorders of HgCl (2)-induced acute renal failure mice. Nephron. 2002 Feb;90(2):195-205.

2(0,0,0,2) Details