| Name | glutathione transferase |
|---|---|
| Synonyms | GST class mu 2; GST 4; GST4; GSTM; GSTM 2; GSTM2; GSTM2 2; GSTmu3… |
| Name | methyl bromide |
|---|---|
| CAS | bromomethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8704864 | Garnier R, Rambourg-Schepens MO, Muller A, Hallier E: Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning. Occup Environ Med. 1996 Mar;53(3):211-15. Seven weeks after the accident, blood samples were drawn from both patients, for measurement of glutathione transferase activity in erythrocytes (conjugator status--that is, GSTT1 phenotype) and measurement of binding products of methyl bromide with blood proteins. |
43(0,1,3,3) | Details |
| 10650922 | Thier R, Wiebel FA, Bolt HM: Differential substrate behaviours of ethylene oxide and propylene oxide towards human glutathione transferase theta hGSTT1-1. Arch Toxicol. 1999 Nov;73(8-9):489-92. This sequence of reactivities of homologous epoxides towards GSTT1-1 contrasts to the sequence observed in homologous alkyl halides (methyl bromide, MBr; ethyl EtBr; n-propyl PrBr) where the relative sequence MeBr >> EtBr > PrBr is observed. |
2(0,0,0,2) | Details |
| 7979958 | Hallier E, Schroder KR, Asmuth K, Dommermuth A, Aust B, Goergens HW: Metabolism of dichloromethane (methylene to in human erythrocytes: influence of polymorphism of glutathione transferase theta (GST T1-1). Arch Toxicol. 1994;68(7):423-7. The formation of from dichloromethane is influenced by the polymorphism of glutathione-S-transferase (GST) Theta, in the same way as the metabolism of methyl bromide, methyl methyl iodide and ethylene oxide. |
1(0,0,0,1) | Details |
| 2347645 | Hallier E, Deutschmann S, Reichel C, Bolt HM, Peter H: A comparative investigation of the metabolism of methyl bromide and methyl iodide in human erythrocytes. Int Arch Occup Environ Health. 1990;62(3):221-5. Inhibition experiments show that a minor form of the erythrocyte glutathione transferase may be responsible for the enzymatic conjugation. |
1(0,0,0,1) | Details |
| 12872524 | Thier R, Bruning T, Roos PH, Rihs HP, Golka K, Ko Y, Bolt HM: Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes. Int J Hyg Environ Health. 2003 Jun;206(3):149-71. Combined genotype analysis of CYP1B1 and the glutathione transferases GSTM1 or GSTT1 has also pointed to interactive effects. Human phenotyping is facilitated by the GST activity towards methyl bromide or ethylene oxide in erythrocytes which is representative of the metabolic GSTT1 competence of the entire organism. |
1(0,0,0,1) | Details |