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Ludbrook J, Graham WF: Mechanical effects of right atrial pressure on heart rate in the conscious rabbit. Aust J Exp Biol Med Sci. 1983 Dec;61 ( Pt 6):675-85.
Then, in addition, the main neurohumoral effects on the cardiac pacemaker were eliminated by three different pharmacologic treatments: (1) the cardiac nerves were blocked by instilling 2% procaine into the pericardial sac, (2) cardiac beta-adrenoceptors and cholinergic receptors were blocked with intravenous propranolol and hyoscine methyl bromide, (3) the above treatments were combined with autonomic ganglion-blockade by intravenous pentolinium. |
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