| Name | alpha1 adrenoceptor (protein family or complex) |
|---|---|
| Synonyms | Alpha adrenoceptor; Alpha adrenoceptor; Alpha adrenergic receptor; Alpha adrenergic receptors; Alpha adrenoceptors; Alpha adrenoceptors; alpha1 Adrenoceptors; alpha1 Adrenoceptor… |
| Name | methyl bromide |
|---|---|
| CAS | bromomethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8201902 | DiCarlo SE, Collins HL, Chen CY: Vagal afferents reflexly inhibit exercise in conscious rats. Med Sci Sports Exerc. 1994 Apr;26(4):459-62. Cardiac autonomic efferent blockade [atropine methyl bromide (14 mg.kg-1, i.v.) and (14 mg.kg-1, i.v.)] and alpha-adrenergic receptor blockade [phenoxybenzamine (5 mg.kg-1, i.v.)] was achieved to prevent bradycardia and hypotension. |
31(0,1,1,1) | Details |
| 11821715 | Tavares RF, Peres-Polon VL, Correa FM: Mechanisms involved in the water intake-related pressor response in the rat. J Hypertens. 2002 Feb;20(2):295-302. The pressor response was significantly reduced by ganglionic blockade with mecamylamine or pretreatment with the alpha1-adrenoceptor antagonist, prazosin. |
2(0,0,0,2) | Details |
| 2555878 | Bertolini A, Ferrari W, Guarini S: The adrenocorticotropic hormone (ACTH)-induced reversal of hemorrhagic shock. Resuscitation. 1989 Dec;18(2-3):253-67. The studies on the mechanism of action indicate that the ACTH-induced reversal of hemorrhagic shock (a) is an extra-hormonal, -independent effect, because it is not affected by adrenalectomy and is shared by many ACTH-fragments practically devoid of corticotropic activity; (b) is antagonized by morphine in a surmontable way; (c) needs the functional integrity of the sympathetic nervous system (it is prevented by guanethidine, reserpine, and clonidine) and the availability of peripheral alpha-adrenoceptors (it is antagonized by dibenamine, prazosin and yohimbine, but not by practolol); (d) requires the integrity of afferent vagal fibers (it is almost completely abolished by vagotomy); (e) involves central cholinergic networks (it is antagonized by atropine sulphate, but not by atropine methyl bromide; and it is prevented by the intracerebroventricular injection of hemicholinium-3); (f) is associated with a massive increase in the volume of circulating blood, likely due to a mobilization from peripheral pooling sites (it is largely prevented by splenectomy or by suprahepatic veins ligature, and is associated with a restoration of the venous blood flow in peripheral vascular beds and with a normalization of venous PO2); (g) is associated with a restoration of heart and spleen adrenoceptors, whose number is significantly decreased during hemorrhagic shock. |
0(0,0,0,0) | Details |